Quantifying Patellar Tendon Microstructure Using Diffusion Tensor Imaging

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Observational
SUMMARY

The goal of this observational study is to understand how diffusion tensor imaging (DTI) relates to other traditional measures and knee function. The main question it aims to answer is: Will regions of known patellar tendon pathology present with smaller DTI scalar parameters, shorter fiber length, and lower fiber density compared to the contralateral tendon and healthy regions in the ipsilateral tendon. Participants will: * undergo MRI and ultrasound imaging * perform knee function test * complete questionnaires

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• Age 18 or older

• Have patellar tendon injury as confirmed through subjective report, clinical examination, and ultrasound by an experienced physical therapist

• Patellar tendinopathy group must present with current symptoms of patellar tendinopathy

• Control group must have no history of patellar tendon injury

Locations
United States
Wisconsin
University of Wisconsin - Madison
RECRUITING
Madison
Contact Information
Primary
Naoaki Ito
ito@ortho.wisc.edu
Time Frame
Start Date: 2024-05-21
Estimated Completion Date: 2025-12
Participants
Target number of participants: 90
Treatments
Bone-patellar tendon-bone (BPTB)
This group will have patellar injury confirmed through self-reported surgical history and evidence of ipsilateral BPTB graft harvest on ultrasound.
Patellar tendinopathy group
This group will have patellar tendinopathy confirmed based on International Scientific Tendinopathy Symposium Consensus on Clinical Terminology (ICON) statement, which defines patellar tendinopathy as persistent patellar tendon pain and loss of function related to mechanical loading. Ultrasound diagnosis must confirm alteration of tendon macrostructure.
Healthy knees
Control group of participants with healthy knees
Related Therapeutic Areas
Sponsors
Leads: University of Wisconsin, Madison
Collaborators: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

This content was sourced from clinicaltrials.gov