Multi-center, Single Arm, Unenhanced MRI-controlled Phase III Study for Efficacy and Safety of MR Arthrography Using the NEMO-103 Injection in Patients With Known or Suspected Shoulder Joint Diseases Requiring MR Arthrography

Status: Recruiting
Location: See all (8) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

The goal of this Phase 3 clinical trial is to evaluate whether MR arthrography enhanced with NEMO-103 injection (NEMO-103 Inj.) provides superior diagnostic imaging quality compared to unenhanced MRI in patients with known or suspected shoulder joint disorders, such as rotator cuff tendon tears, labral tears, and articular cartilage injuries. ⦁ The primary objective is to determine whether NEMO-103 Inj.-enhanced MR arthrography offers improved imaging quality in terms of joint distension, contrast resolution, and image sharpness compared to standard unenhanced MRI. Participation Details: * Each participant will undergo two MRI scans: one unenhanced and one enhanced with NEMO-103 Inj. * NEMO-103 Inj. will be administered once, during the second study visit. * Participants will attend a total of three site visits.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 19
Healthy Volunteers: f
View:

• Age ≥19 years at the time of informed consent.

• Suspected or known shoulder joint diseases requiring MRA for diagnosis or evaluation at screening.

• Voluntarily decided to participate in the study and provided written consent after receiving a sufficient explanation about this study and after fully understanding the information.

Locations
Other Locations
Republic of Korea
Seoul National University Bundang Hospital
RECRUITING
Seongnam-si
Asan Medical Center
RECRUITING
Seoul
Gangnam Severance Hospital
RECRUITING
Seoul
Konkuk University Medical Center
RECRUITING
Seoul
Korea University Guro Hospital
RECRUITING
Seoul
Seoul National University Hospital
RECRUITING
Seoul
The Catholic University of Korea Seoul ST. Mary's Hospital
RECRUITING
Seoul
Yonsei University Health System, Severance Hospital
RECRUITING
Seoul
Contact Information
Primary
Minchang Lee
mclee@inventera.kr
+82 2-533-1103
Time Frame
Start Date: 2025-07
Estimated Completion Date: 2026-08
Participants
Target number of participants: 85
Treatments
Experimental: NEMO-103 Injection
Related Therapeutic Areas
Sponsors
Leads: Inventera Inc.

This content was sourced from clinicaltrials.gov