Florbetaben for Imaging of Vascular Amyloid: Evaluation of Amyloid Inflammasome Imaging in Carotid and Coronary Arteries in Patients With Unstable Atherosclerosis- A Pilot Study
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
The Primary Objective is to determine if a new nuclear tracer (named 18F-Florbetaben) used with nuclear imaging (PET imaging) can detect inflamed plaque in patients with recent ACS or stroke/TIA.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:
• suffered a recent cardiovascular event (30-120 days post ACS (i.e. STEMI or NSTEMI) or TIA/stroke with ipsilateral large vessel atherosclerotic disease confirmed on US, CT or MRI;
• stable symptoms and hemodynamics;
• age \>/= 18 years;
• given informed consent.
Locations
Other Locations
Canada
University of Ottawa Heart Institute
RECRUITING
Ottawa
Contact Information
Primary
Kevin E Boczar, MD
kboczar@ottawaheart.ca
6132821835
Time Frame
Start Date: 2023-10-09
Estimated Completion Date: 2025-08-01
Participants
Target number of participants: 30
Treatments
Acute atherosclerotic disease event group
Patients with a recent ACS (i.e. STEMI or NSTEMI), stroke or transient ischemic attack.
Control
A control population of patients with known vascular disease but without recent ACS, stroke/TIA.
Related Therapeutic Areas
Sponsors
Leads: Ottawa Heart Institute Research Corporation