Effects of Different Doses of Intravenous Lidocaine Infusion on Peri-operative Pain and Incidence of Postoperative Chronic Pain Within ERAS Protocols, a Dose Finding Study.
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 1/Phase 2
SUMMARY
This study aimed To investigate the effects of different doses of Intraoperative intravenous lidocaine infusion on intraoperative opioid consumption, perioperative pain control and incidence of postoperative chronic pain.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: t
View:
• Patients age between 18 and 65.
• Patients with ASA I and II status.
• Patients undergoing open laparotomy surgeries (including open cholecystectomies).
Locations
Other Locations
Egypt
Cairo University
RECRUITING
Cairo
Contact Information
Primary
Alaa Magdy Ahmed Hassan, Master
loka272@yahoo.com
01090282616
Backup
Amany Ezzat Ayad Ibrahim, Professor
amanymounir@kasralainy.edu.eg
01223429325
Time Frame
Start Date: 2024-03-15
Estimated Completion Date: 2025-04
Participants
Target number of participants: 69
Treatments
Active_comparator: Group A
Group A: Bolus 10 ml Syringe with Lidocaine 0.5% (2.5 ml lidocaine 2% + 7.5 ml N.S), and infusion 50 ml Syringe with Lidocaine 0.5% (12.5 ml Lidocaine 2% + 37.5 ml N.S).
Active_comparator: Group B
Group B: Bolus 10 ml Syringe with Lidocaine 1% (5 ml lidocaine 2% + 5 ml N.S), and infusion 50 ml Syringe with Lidocaine 1% (25 ml Lidocaine 2% + 25 ml N.S).
Active_comparator: Group C
Group C: Bolus 10 ml Syringe with plain Lidocaine 2%, and infusion 50 ml Syringe with plain Lidocaine 2%.
Related Therapeutic Areas
Sponsors
Leads: Cairo University