Condition

Adult T-Cell Leukemia

Condition 101

What is the definition of Adult T-Cell Leukemia?

Adult T-cell leukemia/lymphoma (ATL) is is a rare and aggressive T-cell lymphoma that is linked to infection by the human T-cell lymphotropic virus 1 (HTLV-1). The exact mechanism by which HTLV-I infection causes the ATL is unknown. The clinical features of ATL include generalized swel ...

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What are the alternative names for Adult T-Cell Leukemia?

ATLL
Adult T-cell leukaemia
Adult T-cell leukaemia/lymphoma (HTLV-1 positive)
Adult T-cell lymphoma

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Top Global Doctors

Yonashiro-nishihara, 47, JP

Olivier Hermine

Koichi I. Ohshima

Masao Matsuoka

Ali A. Bazarbachi

Thomas P. Loughran

Internal Medicine

Charlottesville, VA

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Latest Research

Latest Advance

Study

Condition: Adults with Tuberculosis/HIV
Journal: The New England journal of medicine
Treatment Used: Systematic vs Test-Guided Treatment
Number of Patients: 522
Published — June 20, 2020

This study compared the effectiveness of systematic (treatment that targets the entire body) versus test-guided treatment for adults with tuberculosis (infectious disease that mainly affects the lungs) and HIV (virus that attacks the body’s immune system).

Latest Advance

Study

Condition: COVID-19 with Severe Systemic Hyperinflammation
Journal: Leukemia
Treatment Used: Ruxolitinib
Number of Patients: 105
Published — June 11, 2020

This study tested the safety and efficacy of using ruxolitinib to treat patients with COVID-19 with severe systemic hyperinflammation.

Latest Advance

Study

Condition: Lymphoma and Leukemia
Journal: Critical reviews in oncology/hematology
Treatment Used: Chimeric Antigen Receptor T-Cell (CAR-T) Therapy
Number of Patients: 0
Published — June 08, 2020

This article updates information on chimeric antigen receptor T-cell (CAR-T) therapy for the treatment of lymphoma and leukemia.

Latest Advance

Study

Condition: T-Cell Acute Lymphoblastic Leukemia
Journal: Cancer medicine
Treatment Used: Cytarabine, Aclarubicin, and G-csf Regimen
Number of Patients: 41
Published — June 04, 2020

In this study, researchers evaluated the outcomes of using the cytarabine, aclarubicin, and G-CSF regimen for the treatment of T-cell acute lymphoblastic leukemia.

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Clinical Trials

Clinical Trial

Drug

Status: Recruiting
Study Type: Drug
Participants: 72
Start Date: August 23, 2020

Clinical Trial for the Safety and Efficacy of CAR-T Cells Therapy for Patients With the Central Nervous System Involvement of Relapsed and/or Refractory B-cell Acute Lymphoblastic Leukemia or B-cell Non-Hodgkin's Lymphoma

Clinical Trial

Drug

Status: Recruiting
Study Type: Drug
Participants: 72
Start Date: August 23, 2020

Clinical Trial for the Safety and Efficacy of Humanized CD19 CAR-T Cells Therapy for Patients With Relapsed and/or Refractory B-cell Acute Lymphoblastic Leukemia and B-cell Non-Hodgkin's Lymphoma

Clinical Trial

Drug

Status: Recruiting
Study Type: Drug
Participants: 120
Start Date: August 23, 2020

Clinical Trial for the Safety and Efficacy of Murine CD19 CAR-T Cells Therapy for Patients With Relapsed and/or Refractory B-cell Acute Lymphoblastic Leukemia and B-cell Non-Hodgkin's Lymphoma

Clinical Trial

Drug

Status: Recruiting
Study Type: Drug
Participants: 61
Start Date: July 14, 2020

A Phase I/II, Multicenter, Open-Label, Nonrandomized Study to Evaluate the Tolerability and Safety of ASTX660 and the Efficacy at the Recommended Dose of ASTX660 in Patients With Relapsed or Refractory T-Cell Lymphoma

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