Adult T-Cell Leukemia
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Adult T-Cell Leukemia Overview

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Learn About Adult T-Cell Leukemia

View Main Condition: Leukemia

What is the definition of Adult T-Cell Leukemia?
Adult T-cell leukemia/lymphoma (ATL) is is a rare and aggressive T-cell lymphoma that is linked to infection by the human T-cell lymphotropic virus 1 (HTLV-1). The exact mechanism by which HTLV-I infection causes the ATL is unknown. The clinical features of ATL include generalized swelling of the lymph nodes (lymphadenopathy), increased liver and spleen size (hepatosplenomegaly), immunosuppression, high levels of calcium in the blood, lytic bone lesions (spots that appear as 'holes' on a standard bone x-ray), and skin lesions. There are four basic clinical variants of ATL: acute (60% of cases), lymphomatous (20 % of cases), chronic (10% of cases) and smoldering (10% of cases).
What are the alternative names for Adult T-Cell Leukemia?
  • Adult T-cell leukemia/lymphoma
  • ATLL
  • Adult T-cell leukaemia
  • Adult T-cell leukaemia/lymphoma (HTLV-1 positive)
  • Adult T-cell lymphoma
Who are the top Adult T-Cell Leukemia Local Doctors?
Elite in Adult T-Cell Leukemia
Elite in Adult T-Cell Leukemia
Referral may be required

Cleveland Clinic

8950 Euclid Ave, 
Cleveland, OH 
216-444-8950
Languages Spoken:
English
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Offers Telehealth

Jaroslaw Maciejewski is a Hematologist practicing medicine in Cleveland, Ohio. Dr. Maciejewski is rated as an Elite provider by MediFind in the treatment of Adult T-Cell Leukemia. He is also highly rated in 25 other conditions, according to our data. His clinical expertise encompasses Paroxysmal Nocturnal Hemoglobinuria (PNH), Aplastic Anemia, Paroxysmal Cold Hemoglobinuria, Bone Marrow Transplant, and Splenectomy.

Distinguished in Adult T-Cell Leukemia
Dr. Adam P. Siegel
Hematology | Oncology
Distinguished in Adult T-Cell Leukemia
Dr. Adam P. Siegel
Hematology | Oncology
Referral required

Vince Lombardi Cancer Clinic

36500 Aurora Dr, 
Summit, WI 
262-434-8800
Experience:
17+ years
Languages Spoken:
English
See accepted insurances
Offers Telehealth

Adam Siegel is a Hematologist and an Oncologist practicing medicine in Summit, Wisconsin. He has been practicing medicine for over 17 years. Dr. Siegel is rated as a Distinguished provider by MediFind in the treatment of Adult T-Cell Leukemia. He is also highly rated in 46 other conditions, according to our data. His clinical expertise encompasses Adult T-Cell Leukemia, Chronic T-Cell Leukemia (CTCL), Angiosarcoma, and Inflammatory Breast Cancer. Dr. Siegel is board certified in American Board Of Internal Medicine, Hematology.

 
 
 
 
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Elite in Adult T-Cell Leukemia
Elite in Adult T-Cell Leukemia
Referral may be required
Kumamoto, JP 

Masao Matsuoka practices practicing medicine in Kumamoto, Japan. Mr. Matsuoka is rated as an Elite expert by MediFind in the treatment of Adult T-Cell Leukemia. He is also highly rated in 8 other conditions, according to our data. His clinical expertise encompasses Adult T-Cell Leukemia, Leukemia, HTLV-1 Associated Myelopathy, Vitrectomy, and Trabeculectomy.

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What are the latest Adult T-Cell Leukemia Clinical Trials?
Immuno-Virological Evaluation of Human T Cell Leukemia Virus Type-1 Associated Myelopathy (HAM/TSP)
Immuno-Virological Evaluation of Human T Cell Leukemia Virus Type-1 Associated Myelopathy (HAM/TSP)
Enrollment Status: Recruiting
Publish Date: June 18, 2026

Objective: Human T-lymphotropic virus type-I-associated myelopathy / tropical spastic paraparesis (HAM/TSP) is a rare neurologic disorder that affects less than 5% of patients infected with the HTLV-I virus. The purpose of this protocol is to study the natural history of HAM/TSP by monitoring clinical progression of patients longitudinally. Additionally, we will attempt to define the virological and immunolo...

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Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy Protocols
Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy Protocols
Enrollment Status: Recruiting
Publish Date: June 18, 2026

Background: Cancer has a major impact in the United States and across the world. In 2015, over 1.5 million new cases of cancer were diagnosed in the U.S. Researchers want to study samples from people with cancer or a pre-malignant condition. They hope to develop more effective treatments.

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center