Learn About AEC Syndrome

What is the definition of AEC Syndrome?
Ankyloblepharon-ectodermal defects-cleft lip/palate syndrome (AEC syndrome)  is a form of ectodermal dysplasia, a group of conditions characterized by abnormal development of ectodermal tissues including the skin, hair, nails, teeth, and sweat glands. The most common feature is missing patches of skin (erosions) on the scalp, neck, hands, and feet. The skin erosions can lead to infection, scarring, and hair loss. Other features include changes in skin coloring; misshapen or absent fingernails and toenails; malformed or missing teeth; increased sensitivity to heat; hearing loss; cleft lip and/or palate; and other facial abnormalities. This condition  is caused by mutations in the TP63 gene and is inherited in an autosomal dominant fashion. Rapp-Hodgkin syndrome was classified as a separate disorder until it was discovered that it result from mutations in the same part of the TP63 gene, and, therefore, most researchers now consider Rapp-Hodgkin syndrome and AEC syndrome to be part of the same disease spectrum.

 

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What are the alternative names for AEC Syndrome?
  • Ankyloblepharon ectodermal defects cleft lip/palate
  • AEC syndrome
  • Hay-Wells syndrome
Who are the top AEC Syndrome Local Doctors?
Distinguished
Highly rated in
3
conditions

Oncode Institute

Amsterdam, NH, NL 

Giustina Ferone is in Amsterdam, Netherlands. Ferone is rated as a Distinguished expert by MediFind in the treatment of AEC Syndrome. She is also highly rated in 3 other conditions, according to our data. Her top areas of expertise are AEC Syndrome, Autosomal Cleft Palate, Aplasia Cutis Congenita, and Clouston Syndrome.

Distinguished
Highly rated in
6
conditions

University Of Naples Federico II

Naples, IT 

Caterina Missero is in Naples, Italy. Missero is rated as a Distinguished expert by MediFind in the treatment of AEC Syndrome. She is also highly rated in 6 other conditions, according to our data. Her top areas of expertise are AEC Syndrome, Aplasia Cutis Congenita, Clouston Syndrome, and Ectodermal Dysplasias.

 
 
 
 
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Distinguished
Highly rated in
8
conditions
Dermatology

Houston, TX 

Alanna Bree is a Dermatologist in Houston, Texas. Dr. Bree is rated as a Distinguished doctor by MediFind in the treatment of AEC Syndrome. She is also highly rated in 8 other conditions, according to our data. Her top areas of expertise are AEC Syndrome, Ectodermal Dysplasias, Clouston Syndrome, and Aplasia Cutis Congenita. She is licensed to treat patients in Texas. Dr. Bree is currently accepting new patients.

What are the latest AEC Syndrome Clinical Trials?
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What are the Latest Advances for AEC Syndrome?

There is no recent research available for this condition. Please check back because thousands of new papers are published every week and we strive to find and display the most recent relevant research as soon as it is available.