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A Non-interventional, Observational Study to Evaluate Treatment Patterns and Safety of Avacincaptad Pegol (ACP/IZERVAY™) in Routine Clinical Practice in Patients With Geographic Atrophy Secondary to Age-related Macular Degeneration

Status: Recruiting
Location: See all (65) locations...
Intervention Type: Drug
Study Type: Observational
SUMMARY

This study is for people who have geographic atrophy due to age-related macular degeneration (AMD). AMD happens when the macula, the light-sensitive layer at the back of the eye called the retina, becomes damaged and causes a person's central vision to worsen. Geographic atrophy is an advanced form of AMD where cells in the retina waste away and die. Over time this can lead to permanent loss of vision. Avacincaptad pegol can help slow down the worsening or progression of geographic atrophy. Avacincaptad pegol is a treatment approved in the US to treat geographic atrophy. This study is about collecting information on how people with geographic atrophy are treated in routine clinical practice. This includes recording any medical problems from avacincaptad pegol. This is known as an observational study. Information will be collected from the peoples' medical records during and after treatment. The people in this study will have geographic atrophy in 1 or both eyes and they and their doctor has decided they will be treated with avacincaptad pegol. The individual's doctor decides on treatment, not the study sponsor (Astellas). People that want to take part in the study will have eye examinations that they would usually have as part of their routine care. People will also be asked to complete surveys about their eye health. These surveys will occur when treatment starts and then every 6 months for the first 2 years. After 2 years the surveys will happen once a year. The people on the study can take part if their doctor provides treatment with avacincaptad pegol and they want to continue with the study. The people on the study can take part for up to 3 years or up to 5 years, depending on when they start the study.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• Patients with geographic atrophy (GA) secondary to age-related macular degeneration (AMD) in 1 or both eyes

• Patient with a decision to treat with intravitreal avacincaptad pegol (ACP) prior to enrollment

• Patient willingness to complete the patient reported outcome (PRO).

Locations
United States
Arizona
Phoenix Retina Clinical Trials, LLC
RECRUITING
Phoenix
Retinal Consultants of AZ
RECRUITING
Phoenix
Retina Macula Institute of Arizona
RECRUITING
Scottsdale
California
The Retina Partners
RECRUITING
Encino
Harvard Eye Associates
RECRUITING
Laguna Hills
University of California Irvine Medical Center
RECRUITING
Orange
Retina Consultants of Southern CA
RECRUITING
Redlands
Retinal Consultants Medical Group Inc
RECRUITING
Sacramento
Retina Macula Institute
RECRUITING
Torrance
Colorado
Rocky Mountain Lions Eye Institute
RECRUITING
Aurora
Retina Consultants of Southern Colorado
RECRUITING
Colorado Springs
Colorado Retina Associates, PLLC
RECRUITING
Lakewood
Connecticut
Coastal Eye Surgeons
RECRUITING
Greenwich
Florida
Florida Eye Clinic
WITHDRAWN
Altamonte Springs
Advanced Retina Institute
RECRUITING
Bonita Springs
University of Miami
RECRUITING
Coral Gables
Retina Care Specialists
RECRUITING
Palm Beach Gardens
Eye Physicians of Pinellas PA dba Eye Institute of West Florida
RECRUITING
Tampa
Retina Specialists of Tampa
RECRUITING
Wesley Chapel
Georgia
Southeast Retina Center, P.C.
RECRUITING
Augusta
Iowa
Wolfe Eye Clinic
RECRUITING
West Des Moines
Illinois
University Retina and Macula Associates, P.C.
RECRUITING
Oak Forest
Illinois Retina Associates
RECRUITING
Oak Park
Illinois Eye Center
RECRUITING
Peoria
Maryland
Cumberland Valley Retina Consultants,P.C.
RECRUITING
Hagerstown
Retina Specialists
RECRUITING
Towson
Michigan
Retina Associates of Michigan
RECRUITING
Grand Blanc
Minnesota
Retina Consultants of Minnesota PLLC
RECRUITING
Saint Louis Park
Mississippi
Mississippi Retina Associates
RECRUITING
Madison
Brown Family Retina PLLC
RECRUITING
Olive Branch
Deep Blue Retina Clinical Research
RECRUITING
Southaven
North Carolina
North Carolina Retina Associates
WITHDRAWN
Cary
North Carolina Retina Associates
RECRUITING
Wake Forest
New Jersey
Eye Associates of North Jersey PA
RECRUITING
Dover
NJ Retina
RECRUITING
Edison
NJ Retina
RECRUITING
Lakewood
Monmouth Retina Consultants
RECRUITING
Little Silver
NJ Retina
RECRUITING
Toms River
Nevada
Sierra Eye Associates
RECRUITING
Reno
New York
SightMD
RECRUITING
Brentwood
Retina-Vitreous Surgeons of Central NY
RECRUITING
Liverpool
NY Retina Ophthalmology PLLC
ACTIVE_NOT_RECRUITING
Massapequa
Retina Associates of New York
ACTIVE_NOT_RECRUITING
New York
Long Island Vitreoretinal Consultants
RECRUITING
Scarsdale
Vitreoretinal Consultants
RECRUITING
Shirley
Ohio
The Ohio State University
RECRUITING
Columbus
CEI Physicians PSC, LLC dba
RECRUITING
Dayton
Oregon
Verum Research, LLC
RECRUITING
Eugene
Pennsylvania
Erie Retina Research
RECRUITING
Erie
Tennessee
Southeastern Retina Associates, P.C.
RECRUITING
Knoxville
Southeastern Retina Associates, P.C.
RECRUITING
Knoxville
Mid South Retina Associates
RECRUITING
Memphis
Tennessee Retina, PC
RECRUITING
Nashville
Texas
Retina Research Institute of Texas
RECRUITING
Abilene
Retina & Vitreous of Texas
WITHDRAWN
Bellaire
Retina of North Texas
RECRUITING
Dallas
Valley Retina Institute
RECRUITING
Mcallen
Medical Center Ophthalmology Associates
RECRUITING
San Antonio
Retina Associates Of South Texas, Pa
RECRUITING
San Antonio
Utah
Retina Associates of Utah, P.C.
RECRUITING
Murray
Salt Lake Retina
RECRUITING
Salt Lake City
Virginia
The Retina Group of Washington
RECRUITING
Fairfax
Piedmont Eye Center, Inc.
RECRUITING
Lynchburg
Virginia Retina Center
RECRUITING
Warrenton
Wisconsin
Retina & Vitreous Consultants of Wisconsin
ACTIVE_NOT_RECRUITING
Milwaukee
Contact Information
Primary
Astellas Pharma Global Development, Inc.
Astellas.registration@astellas.com
800-555-5555
Time Frame
Start Date: 2025-01-22
Estimated Completion Date: 2030-01-31
Participants
Target number of participants: 1000
Treatments
Izervay
Patients with geographic atrophy (GA) secondary to AMD who have made decision to begin treatment with Izervay
Related Therapeutic Areas
Geographic Atrophy
Late-Onset Retinal Degeneration
Age-Related Macular Degeneration (ARMD)
Sponsors
Leads: Astellas Pharma Global Development, Inc.

This content was sourced from clinicaltrials.gov

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