Minimal Vitrectomy Surgery (MVS) Versus Conventional Vitrectomy for the Treatment of Idiopathic Epiretinal Membrane: A Multicenter Randomized Controlled Trial
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This multicenter randomized controlled trial evaluates Minimal Vitrectomy Surgery (MVS) versus conventional vitrectomy for idiopathic epiretinal membrane (ERM). The primary endpoints include visual acuity improvement and cataract progression after 12 months. MVS aims to minimize vitreous removal while ensuring complete membrane removal through adaptive limited vitrectomy.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age ≥ 18 years.
• Diagnosis of idiopathic epiretinal membrane (ERM) confirmed by clinical examination and OCT imaging.
• Clear ocular media allowing adequate fundus imaging.
• Phakic eye.
• Ability and willingness to provide written informed consent.
Locations
Other Locations
China
Peking Union Medical College Hospital
RECRUITING
Beijing
Contact Information
Primary
Weihong Yu, MD
yuweihongpumch@163.com
+8613671214306
Backup
Xufeng Zhao
yezhong019@163.com
+8619121036553
Time Frame
Start Date: 2024-12-01
Estimated Completion Date: 2026-11-30
Participants
Target number of participants: 140
Treatments
Experimental: Minimal Vitrectomy Surgery (MVS)
The epiretinal membrane is peeled directly through the intact vitreous. Limited vitrectomy is selectively performed if pre-existing floaters or membrane fragments remain after peeling and cannot be removed safely with forceps.
Active_comparator: Conventional Vitrectomy (PPV)
Standard pars plana vitrectomy is performed. Posterior vitreous detachment induction and core vitreous removal are conducted before membrane peeling.
Related Therapeutic Areas
Sponsors
Collaborators: Peking Union Medical College
Leads: Peking Union Medical College Hospital