The Prevalence of Ethnic Neutropenia in Neonates

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

This is a prospective observational study designed to assess the prevalence of the Duffy null phenotype (associated with ethnic neutropenia) in neonates born at Kaplan Medical Center. Blood samples will be collected from umbilical cords (non-invasively) to evaluate Duffy antigen expression. Data on ethnicity, perinatal factors, and routine blood counts at 9-12 months (when available) will also be collected to correlate phenotype with absolute neutrophil count (ANC).

Eligibility
Participation Requirements
Sex: All
Minimum Age: Newborn
Maximum Age: 1 day
Healthy Volunteers: f
View:

• Neonates born at Kaplan Medical Center between 1.9.2024 and 31.12.2025

• Parental informed consent obtained

• Umbilical cord blood available for routine testing

Locations
Other Locations
Israel
Kaplan Medical Center
RECRUITING
Rehovot
Contact Information
Primary
Tal Ben Ami, M.D
tal.ben.ami11@gmail.com
+972-50-7414922
Backup
Yael Zeitak, PhD
yaelze4@clalit.org.il
+972-52-627-4987
Time Frame
Start Date: 2024-10-08
Estimated Completion Date: 2027-12-31
Participants
Target number of participants: 1000
Treatments
Neonatal birth cohort
Neonates born at Kaplan Medical Center whose cord blood is tested for Duffy antigen status and complete blood count. Follow-up neutrophil data is collected at 9-12 months if available.
Related Therapeutic Areas
Sponsors
Leads: Kaplan Medical Center

This content was sourced from clinicaltrials.gov