Aicardi-Goutieres Syndrome Latest Advances

Find the Latest Research About Aicardi-Goutieres Syndrome

Last Updated: 09/26/2026

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Found 386 publications

Type I interferonopathies: 15 years after the concept-news and views.

Type I interferonopathies: 15 years after the concept-news and views.

Journal: Current opinion in rheumatology

Published: July 18, 2026

MDA5 and the integrated stress response control sex-specific type 1 diabetes onset in NOD mice.

MDA5 and the integrated stress response control sex-specific type 1 diabetes onset in NOD mice.

Journal: bioRxiv : the preprint server for biology

Published: July 17, 2026

Design, Synthesis, and Pharmacological Evaluation of cGAS/HDAC Dual Inhibitors for Treatment of Autoimmune Diseases.

Design, Synthesis, and Pharmacological Evaluation of cGAS/HDAC Dual Inhibitors for Treatment of Autoimmune Diseases.

Journal: Journal of medicinal chemistry

Published: June 10, 2026

Neonatal Aicardi-Goutières syndrome presenting with macrophage activation syndrome-like hyperinflammation and severe congenital glaucoma: a case report.

Neonatal Aicardi-Goutières syndrome presenting with macrophage activation syndrome-like hyperinflammation and severe congenital glaucoma: a case report.

Journal: Pediatric rheumatology online journal

Published: June 08, 2026

Spastic Hip Dislocation in a Child With Aicardi-Goutières Syndrome: A Case Report.

Spastic Hip Dislocation in a Child With Aicardi-Goutières Syndrome: A Case Report.

Journal: JBJS case connector

Published: April 15, 2026

Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi-Goutières syndrome neuropathology.

Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi-Goutières syndrome neuropathology.

Journal: eLife

Published: January 27, 2026

Monogenic and SLE-like disorders in the pediatric population: insights from a Northern Israel cohort.

Monogenic and SLE-like disorders in the pediatric population: insights from a Northern Israel cohort.

Journal: Lupus

Published: January 14, 2026

Beyond the interferon score: neurofilament light chain and glial fibrillary acidic protein capture immune-mediated neuroinjury and response to JAK inhibition in Aicardi-Goutières syndrome.

Beyond the interferon score: neurofilament light chain and glial fibrillary acidic protein capture immune-mediated neuroinjury and response to JAK inhibition in Aicardi-Goutières syndrome.

Journal: Frontiers in immunology

Published: January 06, 2026

Aicardi-Goutières Syndrome caused by SAMHD1 mutation: Pathogenesis and Beyond.

Aicardi-Goutières Syndrome caused by SAMHD1 mutation: Pathogenesis and Beyond.

Journal: Clinical immunology (Orlando, Fla.)

Published: December 11, 2025

Efficacy of JAK1/2 inhibitors in AGS genes-related interferonopathies: A multicenter retrospective observational study with treated vs untreated comparison.

Efficacy of JAK1/2 inhibitors in AGS genes-related interferonopathies: A multicenter retrospective observational study with treated vs untreated comparison.

Journal: Molecular genetics and metabolism

Published: December 05, 2025

Context-dependent effects of adaptive immunity on IFN-α-mediated neurotoxicity in Aicardi-Goutières syndrome.

Context-dependent effects of adaptive immunity on IFN-α-mediated neurotoxicity in Aicardi-Goutières syndrome.

Journal: Neurobiology of disease

Published: November 24, 2025

Pharmacological stabilization of hypoxia-inducible factor 1-α dampens the interferon response and promotes glycolysis in Aicardi-Goutières syndrome.

Pharmacological stabilization of hypoxia-inducible factor 1-α dampens the interferon response and promotes glycolysis in Aicardi-Goutières syndrome.

Journal: Nature communications

Published: November 04, 2025

Showing 1-12 of 386

Last Updated: 09/26/2026