Low Systemic/High Local Exercise Load in Pediatric Sickle Cell Disease

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This research study wants to learn about what kind of exercise is best for kids with sickle cell disease. Participating children will have a small amount of blood drawn one time at the beginning of the study. Children will then complete some questionnaires that measure pain, physical function, and emotions (depression, anxiety) and complete some tests that measure physical fitness at the beginning and end of the study. Children will be randomized to either a home-based telehealth (1) walking or (2) strengthening exercise program that lasts for 8-weeks, 3-x week, for 45 minutes each session. Children's participation will last up to 10 weeks.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 12
Maximum Age: 17
Healthy Volunteers: t
View:

• youth 12 to 17 years old

• diagnosed with SCD genotype SS, SC, beta-plus thalassemia, or beta-zero thalassemia

• has daily access to an Internet enabled device (e.g., smart phone, IPad) A parent (≥21 years old) will also be recruited for each youth participant.

Locations
United States
Mississippi
University of Mississippi Medical Center
RECRUITING
Jackson
Contact Information
Primary
Cynthia W Karlson, PhD
ckarlson@umc.edu
6019842723
Backup
Rhonda Aikens
raikens@umc.edu
601-984-2716
Time Frame
Start Date: 2023-09-19
Estimated Completion Date: 2025-06-30
Participants
Target number of participants: 60
Treatments
Experimental: Low systemic strength training
8-week (3 times per week; 45-minute sessions) home-based telehealth strengthening exercise program
Experimental: Moderate systemic exercise
8-week (3 times per week; 45-minute sessions) home-based telehealth walking protocol
Sponsors
Collaborators: University of Alabama at Birmingham
Leads: University of Mississippi Medical Center

This content was sourced from clinicaltrials.gov