Condition 101 About Hemoglobinopathy

What is the definition of Hemoglobinopathy?

Hemoglobinopathy is a group of disorders in which there is abnormal production or structure of the hemoglobin molecule. It is passed down through families (inherited).

This group of disorders includes hemoglobin C disease, hemoglobin S-C disease, sickle cell anemia, and thalassemias.

REFERENCES

Howard J. Sickle cell disease and other hemoglobinopathies. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 154.

Smith-Whitley K, Kwiatkowski JL. Hemoglobinopathies. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 489.

Latest Advances On Hemoglobinopathy

  • Condition: Thalassemia
  • Journal: Blood advances
  • Treatment Used: Luspatercept
  • Number of Patients: 336
  • Published —
The study researched the use of luspatercept for patients with thalassemia.
  • Condition: Sickle Cell Disease
  • Journal: Blood advances
  • Treatment Used: Allogeneic Stem Cell Transplantation with Omidubicel
  • Number of Patients: 13
  • Published —
This study tested the safety and efficacy of using allogeneic stem cell transplantation with omidubicel to treat patients with sickle cell disease.

Clinical Trials For Hemoglobinopathy

Clinical Trial
  • Status: Not yet recruiting
  • Phase: Phase 2
  • Intervention Type: Dietary Supplement, Drug
  • Participants: 100
  • Start Date: July 2021
Management of Severe Acute Malnutrition in Children With Sickle Cell Disease Greater Than 5 Years of Age Living in Northern Nigeria
Clinical Trial
  • Status: Not yet recruiting
  • Intervention Type: Diagnostic Test
  • Participants: 100
  • Start Date: June 1, 2021
Thrombophilia Versus Platelet Dysfunction In Beta Thalassemia