Study of Translational Process of Relationship Between Intestinal Microbiota of Dysbiosis and the Psychic Symptoms of Anorexia Nervosa (Eating Disorders and Anxio-depression Disorders)

Status: Recruiting
Location: See location...
Intervention Type: Biological
Study Type: Observational
SUMMARY

The purpose of this study will be to study the association between the level of psychic symptomatic of anorexia nervosa (AN) (intensity of food restriction, symptoms of anxiety and depression) and alteration of host environment symbiosis and the mechanism (dysbiosis of intestinal microbiota, increase of intestinal permeability, immunity alteration and low-grade inflammation).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

⁃ For patients:

• Patients aged ≥18 years;

• Anorexia according to DSM-5 and CIDI (Composite International Diagnostic Interview);

• Body mass index (BMI) (P/T2) \< 15;

• Hospitalization for nutrition rehabilitation;

• Covered by a health insurance;

• Informed consent form signed.

⁃ For Healthy Volunteers:

• Aged ≥18 years;

• 18.5 \< BMI (P/T2) \< 25;

• Covered by a health insurance;

• Informed consent form signed.

Locations
Other Locations
France
Service de Nutrition Clinique, Hôpital Paul Brousse (APHP)
RECRUITING
Villejuif
Contact Information
Primary
Mouna HANACHI GUIDOUM, MD
mouna.hanachi@aphp.fr
+ 33 6 70 39 42 37
Backup
Joël DORE
joel.dore@jouy.inrae.fr
+ 33 1 34 65 27 09
Time Frame
Start Date: 2024-05-23
Estimated Completion Date: 2025-07
Participants
Target number of participants: 120
Treatments
Anorexia patients
Hospitalized anorexia patients with body mass index \< 15.
Healthy controls
Health volunteers: 18 years or older with body mass index between 18.5 and 25.
Related Therapeutic Areas
Sponsors
Leads: Assistance Publique - Hôpitaux de Paris
Collaborators: Fondation de France

This content was sourced from clinicaltrials.gov