Food Intake and IgA Microbiota in Anorexia Nervosa

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Anorexia nervosa is characterized by intestinal dysbiosis, related to the feeding behavior impairment presented by these patients. Pathophysiologic hypotheses are involving the trouble of the microbiota-gut-brain axis in the field of mental diseases.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 50
Healthy Volunteers: t
View:

• female subject, adult, affiliated to a social security system, under the care of the eating disorder department of university hospital of st Etienne

• presenting a diagnosis of pure restrictive anorexia nervosa.

⁃ For acute subgroup : BMI between 11 and 17.5 kg/m2, patient with a first episode of restrictive anorexia nervosa or with hyperphagic episodes.

⁃ For the chronic subgroup: BMI between 11 and 17.5 kg/m2, disease evolving for more than 5 years.

⁃ For Healthy volunteer: BMI between 20 and 24 kg/m², stable weight for the last 3 months, no eating disorder or history of eating disorder

Locations
Other Locations
France
Chu Saint-Etienne
RECRUITING
Saint-etienne
Contact Information
Primary
Tristan GABRIEL-SEGARD, Md
Tristan.Gabriel-Segard@chu-st-etienne.fr
04 77 12 02 61
Time Frame
Start Date: 2023-10-13
Estimated Completion Date: 2025-09-30
Participants
Target number of participants: 80
Treatments
Experimental: Acute anorexia nervosa
patient diagnose for a first episode of pure restrictive anorexia nervosa will be included. They will have stool sample and Food intake evaluation.
Experimental: Chronic anorexia nervosa
Patient diagnose for anorexia nervosa at least 5 years ago and still maintaining a significant thinness will be included. They will have stool sample and Food intake evaluation.
Placebo_comparator: Healthy control
Healthy Patient will be included. They will have stool sample and Food intake evaluation.
Related Therapeutic Areas
Sponsors
Collaborators: Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Laboratory Physiopathologie et biotherapies des infections muqueuses (GIMAP)
Leads: Centre Hospitalier Universitaire de Saint Etienne

This content was sourced from clinicaltrials.gov