Eating Disorders Genetics Initiative 2

Status: Recruiting
Location: See all (5) locations...
Intervention Type: Other
Study Type: Observational
SUMMARY

The overarching intention of the Eating Disorder Genetics Initiative 2 (EDGI2) is to increase sample size, diversity, and eating disorder phenotypes. The investigators are enrolling 20,000 new participants with anorexia nervosa (AN), bulimia nervosa (BN), binge-eating disorder (BED), avoidant/restrictive food intake disorder (ARFID), and controls in the US, Mexico, Australia, New Zealand, Sweden, and Denmark. A primary study goal is to enroll at least 30% of participants from underrepresented groups. Participants are asked to complete a series of questionnaires and submit a saliva sample for genotyping. The goal is to better understand eating disorders and how they relate to each other so that better treatments can be developed.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 12
Maximum Age: 99
Healthy Volunteers: t
View:

• A lifetime history of anorexia nervosa, bulimia nervosa, binge-eating disorder, avoidant restrictive food intake disorders or no history of any disordered eating behavior, based on DSM-5 criteria algorithms

• Age 12-99 years, depending on country. (US enrollment age is 18-99)

Locations
United States
North Carolina
University of North Carolina at Chapel Hill
RECRUITING
Chapel Hill
Other Locations
Australia
QIMR Berghofer
RECRUITING
Brisbane
Mexico
Comenzar de Nuevo
RECRUITING
Monterrey
New Zealand
University of Otago
RECRUITING
Christchurch
Sweden
Karolinska Institutet
RECRUITING
Stockholm
Contact Information
Primary
Laura M Thornton, PhD
laura_thornton@med.unc.edu
804-690-3079
Backup
Casey MacDermod, BA
edgi2@unc.edu
984-974-3798
Time Frame
Start Date: 2024-10-28
Estimated Completion Date: 2027-08-01
Participants
Target number of participants: 20000
Treatments
Anorexia nervosa
Individuals with a self-reported lifetime history of anorexia nervosa.
Bulimia nervosa
Individuals with a self-reported lifetime history of bulimia nervosa.
Binge-eating disorder
Individuals with a self-reported lifetime history of binge-eating disorder.
ARFID
Individuals with a self-reported lifetime history of avoidant restrictive food intake disorder.
Control
Individuals with no history of disordered eating behaviors or symptoms
Related Therapeutic Areas
Sponsors
Collaborators: Yale University, Karolinska Institutet, University of Aarhus, National Institute of Mental Health (NIMH), University of Sydney, Queensland Institute of Medical Research, Comenzar de Nuevo, AC, University of Otago
Leads: University of North Carolina, Chapel Hill

This content was sourced from clinicaltrials.gov