Pediatric POTS: Does a Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Natural History With Its Numerous Co-morbidities?
Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study is being conducted to see how people with Postural tachycardia syndrome (POTS) make sense of the things they see. The information may help doctors to learn more about how the different parts of people's brains communicate.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 12
Maximum Age: 21
Healthy Volunteers: t
View:
• Females 12-21 years old
• Able to communicate and provide consent/assent
• English speaking
• Diagnosed with POTS (POTS will be defined standardly as a symptomatic ≥ 40 bpm rise in heart rate without a drop in blood pressure and with symptoms of orthostatic intolerance clinically)
• Age-matched healthy control subjects: no POTS or other neurological disorders
Locations
United States
Virginia
Virginia Commonwealth University
RECRUITING
Richmond
Contact Information
Primary
Gisela Chelimsky, M.D.
gisela.chelimsky@vcuhealth.org
(804) 628-0145
Backup
Madison Maxwell, B.S.
madison.maxwell@vcuhealth.org
Time Frame
Start Date: 2023-03-06
Estimated Completion Date: 2025-12
Participants
Target number of participants: 36
Treatments
Other: Adolescents with POTS
Other: Adolescents without POTS
Related Therapeutic Areas
Sponsors
Leads: Virginia Commonwealth University