Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia

Status: Recruiting
Location: See all (5) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Sphere-9 VT EFS is a prospective, multi-center, non-randomized, unblinded feasibility study. Adult subjects with recurrent, sustained, monomorphic ventricular tachycardia due to prior myocardial infarction will be enrolled and treated with the Sphere-9 Catheter and Affera Ablation System.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: f
View:

• Prior myocardial infarction (MI).

• At least one episode of sustained (continuous for \>30 seconds or requiring ICD intervention for termination) monomorphic ventricular tachycardia within the 6 months prior to enrollment.

• Recurrence of sustained ventricular tachycardia despite class I or III antiarrhythmic drug therapy or ICD intervention.

• Implanted with an implantable cardiac defibrillator (ICD) or CRT-D for at least 3 months prior to the ablation procedure.

• Age 18 through 85 years old.

• Willing and able to provide informed consent.

• Willing and able to comply with all pre-, post-, and follow-up testing requirements.

Locations
United States
Massachusetts
Beth Israel Deaconess Medical Center
RECRUITING
Boston
New York
Icahn School of Medicine at Mount Sinai
RECRUITING
New York
Ohio
Cleveland Clinic Foundation
ACTIVE_NOT_RECRUITING
Cleveland
Pennsylvania
Hospital of the University of Pennsylvania
RECRUITING
Philadelphia
Tennessee
Vanderbilt University Medical Center
RECRUITING
Nashville
Contact Information
Primary
Josh Treadway
josh.b.treadway@medtronic.com
817-412-0608
Time Frame
Start Date: 2025-03-18
Estimated Completion Date: 2026-06
Participants
Target number of participants: 40
Treatments
Experimental: Ventricular tachycardia catheter ablation
Ablation using the Sphere-9 Catheter with the Affera Mapping and Ablation System
Sponsors
Leads: Medtronic Cardiac Ablation Solutions

This content was sourced from clinicaltrials.gov