Autologous Adipose-derived Stromal Vascular Fraction Therapy for Refractory Endometrial Infertility
Status: Recruiting
Location: See location...
Intervention Type: Biological
Study Type: Interventional
Study Phase: Phase 1
SUMMARY
The purpose of this study is to initially explore the efficacy of adipose-derived stromal vascular fraction (AD-SVF) therapy in the treatment of refractory endometrial infertility.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 22
Maximum Age: 45
Healthy Volunteers: f
View:
• refractory thin endometrium (endometrial thickness \< 6 mm on the day of ovulation or the day of endometrial transformation during a hormone replacement cycle) and/or moderate to severe intrauterine adhesion；
• Inability to undergo autologous bone marrow stem cells-scaffold (BMSC) transplantation due to failed bone marrow aspiration, or lack of significant effect following the BMSC treatment;
• with fertility intentions;
• normal ovarian function or availability of cryopreserved embryos;
• 18kg/m\^2 \< body mass index (BMI) \< 30kg/m\^2;
Locations
Other Locations
China
Nanjing Drum Tower Hospital
RECRUITING
Nanjing
Contact Information
Primary
Yali Hu
glyyhuyali@163.com
86-025-83106666
Backup
Hui Zhu
zhuhui1231@126.com
86-025-83106666
Time Frame
Start Date: 2025-11
Estimated Completion Date: 2027-06
Participants
Target number of participants: 10
Treatments
Experimental: AD-SVF therapy
AD-SVF intrauterine infusion therapy
Related Therapeutic Areas
Sponsors
Leads: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School