Bi-atrial Versus Left Atrial Ablation for Patients With Rheumatic Mitral Valve Disease and Non-paroxysmal Atrial Fibrillation: a Multicenter, Prospective, Randomized Controlled Trial
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study is aimed to compare the efficacy of bi-atrial ablation with left atrial ablation for atrial fibrillation during mitral valve surgery in patients with rheumatic mitral valve disease.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age ≥ 18 years
• Diagnosis of persistent atrial fibrillation(AF) or long-standing persistent AF by medical history and Holter monitoring (persistent AF lasting more than 7 days; long-standing persistent AF lasting more than 1 year).
• Rheumatic mitral valve disease(RMVD) requires mitral valve surgery( RMVD was determined by history of acute rheumatic fever, valve morphology, echocardiographic findings and pathological diagnosis).
• Consent to surgical ablation of AF
Locations
Other Locations
China
Fuwai Hospital
RECRUITING
Beijing
Nanjing First Hospital, Nanjing Medical University
RECRUITING
Nanjing
Contact Information
Primary
Zhe Zheng, MD,PhD
zhengzhe@fuwai.com
: +86-010-88396051
Backup
Chunyu Yu, MD
yuchunyu@fuwai.com
Time Frame
Start Date: 2022-05-10
Estimated Completion Date: 2025-07
Participants
Target number of participants: 320
Treatments
Experimental: Bi-atrial ablation group
Participants in this group will receive mitral valve surgery concomitant with bi-atrial ablation procedure.
Active_comparator: Left atrial ablation group
Participants in this group will receive mitral valve surgery concomitant with left atrial ablation procedure.
Related Therapeutic Areas
Sponsors
Leads: China National Center for Cardiovascular Diseases