PARALELL - Pulsed Field Ablation and Pulsed Field CRyoAbLation in PErsistent AtriaL FibrilLation

Status: Unknown
Location: See all (5) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

A prospective, two-arm, multi-center, randomized, open-label, pre-market, First-in-Human clinical study designed to provide safety and performance data regarding the use of the Adagio PFA and PFCA Systems in the treatment of PsAF.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• IC 1 Male or female between the ages of 18 - 80 years

• IC 2 Currently scheduled for an ablation of symptomatic persistent (\> 7 days) atrial fibrillation within the past year documented by ECG or Continuous Holter monitoring

• IC 3 Refractory to at least one class I or III AAD. (Refractory defined as not effective or not tolerated)

• IC 4 Willingness, ability, and commitment to participate in baseline and follow-up evaluations for the full length of the study

• IC 5 Willingness and ability to give an informed consent

Locations
Other Locations
Belgium
Onze-Lieve-Vrouwziekenhuis (OLV)
RECRUITING
Aalst
Canada
McGill University Health Centre (MUHC), Montreal General Hospital (MGH)
RECRUITING
Montreal
Ireland
Blackrock Health
RECRUITING
Dublin
Netherlands
St Antonius Ziekenhuis
RECRUITING
Nieuwegein
United Kingdom
St George'S University Hospital
RECRUITING
London
Contact Information
Primary
Nabil Jubran
njubran@adagiomedical.com
9493481188
Backup
Doug Kurschinski
dkurschinski@adagiomedical.com
9493481188
Time Frame
Start Date: 2022-10-20
Completion Date: 2025-05-01
Participants
Target number of participants: 78
Treatments
Experimental: Pulsed Field Ablation (PFA) group
PsAF patients treated by PFA
Experimental: Pulsed Field CryoAblation (PFCA) group
PsAF patients treated by PFCA
Related Therapeutic Areas
Sponsors
Leads: Adagio Medical

This content was sourced from clinicaltrials.gov