Pericardiotomy in Cardiac Surgery Trial
Status: Recruiting
Location: See all (4) locations...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
PRINCE is an international, multicentre, randomized controlled trial of posterior pericardiotomy in patients without a history of atrial fibrillation (AF) or flutter undergoing cardiac surgery.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Patients greater than or equal to 18 years of age
• Requiring surgical intervention on the proximal aorta, cardiac valves, and/or coronary arteries
• Able to provide informed consent
Locations
United States
New York
Weill Cornell Medicine
RECRUITING
New York
Other Locations
Austria
Medical University Vienna
RECRUITING
Vienna
Canada
Hamilton Health Sciences
RECRUITING
Hamilton
Italy
University of Foggia, Policlinico Foggia
RECRUITING
Foggia
Contact Information
Primary
Richard Whitlock
Richard.Whitlock@phri.ca
9055274322
Backup
PRINCE Coordinators
PRINCE@phri.ca
Time Frame
Start Date: 2024-10-21
Estimated Completion Date: 2031-09-01
Participants
Target number of participants: 1400
Treatments
Experimental: Left Posterior Pericardiotomy Group
The surgeon will perform a left posterior pericardiotomy during the patient's cardiac surgery.
No_intervention: No Posterior Pericardiotomy Group
The surgeon will not perform a posterior pericardiotomy during the patient's cardiac surgery.
Related Therapeutic Areas
Sponsors
Collaborators: Weill Medical College of Cornell University, Hamilton Health Sciences Corporation, McMaster University
Leads: Population Health Research Institute