Transcranial Electrical Stimulation Modalities for the Treatment of Clinical Symptoms and Cognitive Deficits in Attention-deficit Hyperactivity Disorder Disorder
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This project investigates the efficacy of transcranial electrical stimulation (tES) modalities, specifically transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS), for treating Attention-Deficit/Hyperactivity Disorder (ADHD) in children and adolescents.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 7
Maximum Age: 18
Healthy Volunteers: f
View:
• Diagnosis of ADHD by a licensed psychiatrist and a behavioral checklist
• being 7-18 years old
• providing written informed consent signed by parents
Locations
Other Locations
Islamic Republic of Iran
Institute for Research in Fundamental Sciences
RECRUITING
Tehran
Contact Information
Primary
Mohammad Ali Salehinejad Haghighi
salehinejadmohammadali@gmail.com
017642062686
Time Frame
Start Date: 2025-03-30
Estimated Completion Date: 2026-07-01
Participants
Target number of participants: 45
Treatments
Active_comparator: active tDCS group
This group receives Transcranial Direct Current Stimulation (tDCS). tDCS delivers a constant, low-intensity direct current (typically 1-2 mA) through electrodes placed on the scalp. The anode (positive electrode) increases cortical excitability by depolarizing neurons, while the cathode (negative electrode) decreases excitability by hyperpolarizing neurons.
Active_comparator: active tACS group
This group receives Transcranial Alternating Current Stimulation (tACS). tACS applies an oscillating current at specific frequencies (e.g., 1-100 Hz) to entrain or synchronize neural oscillations. By aligning the stimulation frequency with endogenous brain rhythms (e.g., theta or gamma bands), tACS can modulate network dynamics, potentially normalizing aberrant oscillatory patterns associated with disorders like ADHD.
Placebo_comparator: sham group
This group receives sham stimulation. The stimulation duration is for 1 minuetand the device will be turned off after the stimulation
Related Therapeutic Areas
Sponsors
Leads: The National Brain Mapping Laboratory (NBML)
Collaborators: RWTH Aachen University, Institute for Research in Fundamental Sciences, Leibniz Research Centre for Working Environment and Human Factors