Cerebellum and Autism: Regional Specialization for Social and Executive Functions

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this study is to determine the impact of neuromodulation to the cerebellum on social and executive functions in neurotypical young adults and young adults with autism.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 35
Healthy Volunteers: t
View:

⁃ All participants

• Aged 18-35

• Able to provide written, informed consent

• NIH Toolbox age-adjusted Cognitive Function Composite standard score ≥ 85

• Native English speaker

• Right-handed

• Not pregnant

• Able to attend all study sessions

• Pass safety screening for MRI and neuromodulation (e.g. no metal in body, implanted devices, history of seizure, claustrophobia)

⁃ Additional INCLUSION criteria for adults with autism Either

• Prior research-reliable diagnosis of autism spectrum disorder (ASD) Or

• Meet DSM-5 criteria for ASD confirmed with ADOS-2 via research-reliable clinical assessment

Locations
United States
Washington, D.c.
American University
RECRUITING
Washington D.c.
Contact Information
Primary
Catherine Stoodley, D.Phil.
stoodley@american.edu
202-476-4799
Backup
Joe Dust, M.Sc.
jd7958a@american.edu
Time Frame
Start Date: 2022-01-01
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 80
Treatments
Experimental: Right cerebellum
Participants (neurotypical, autistic) in this arm will receive tDCS targeting the right posterolateral cerebellum (lobule VII). All participants will receive anodal, cathodal and sham tDCS.
Experimental: Posterior vermis
Participants (neurotypical, autistic) in this arm will receive tDCS targeting the posterior cerebellar vermis. All participants will receive anodal, cathodal and sham tDCS.
Authors
Catherine Stoodley
Related Therapeutic Areas
Autism Spectrum Disorder
Sponsors
Leads: American University
Collaborators: National Institute of Mental Health (NIMH), National Institutes of Health (NIH)

This content was sourced from clinicaltrials.gov

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