Internet-delivered Cognitive-behaviour Therapy for Obsessive- Compulsive Disorder in Children With Autism: A Randomised Controlled Trial

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this trial is to evaluate the clinical efficacy, the cost-effectiveness and the effect durability of a therapist-guided, internet-delivered cognitive-behavior therapy intervention for obsessive-compulsive disorder (OCD) in children and adolescents with autism. A process evaluation of the treatment will also be conducted.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 7
Maximum Age: 17
Healthy Volunteers: f
View:

• A diagnosis of autism, based on the diagnostic criteria of the 4th or 5th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM) or the 10th edition of the International Classification of Diseases (ICD-10). Informed by the parent/caregiver and subsequently confirmed by review of the medical record or the neurodevelopmental assessment report. A diagnosis of autism will be considered present if it was established with validated instruments, such as the Autism Diagnostic Interview-Revised (ADI-R), the Autism Diagnostic Observation Schedule (ADOS) edition 1 or 2 or the Diagnostic Interview for Social and Communication Disorders (DISCO; autism or ASD cut-offs).

• A DSM-5 or ICD-10 diagnosis of OCD. Confirmed by the assessor at the inclusion assessment, based on a structured diagnostic interview.

• A total score of ≥16 on the CY-BOCS. Confirmed by the assessor at the inclusion assessment.

• Age between 7 and 17 years. Confirmed by the caregiver and subsequently by the medical record system.

• Ability to read and write Swedish. Confirmed by the caregiver at the telephone screening or/and the inclusion assessment.

• Regular access to a computer or a smartphone/tablet connected to the internet, and a mobile phone to receive text messages. Confirmed by the caregiver at the telephone screening or/and inclusion assessment.

• A parent/caregiver able to participate in the treatment alongside their child. Confirmed by the caregiver at the telephone screening or/and the inclusion assessment.

Locations
Other Locations
Sweden
BUP Specialmottagning
RECRUITING
Gothenburg
Forskningsmottagning barn- och ungdomspsykiatri Lund
RECRUITING
Lund
Child and Adolescent Psychiatry Research Center
RECRUITING
Stockholm
Contact Information
Primary
David Mataix-Cols
david.mataix.cols@ki.se
+46723986889
Backup
Moa Warnström
moa.warnstrom@ki.se
+46768419808
Time Frame
Start Date: 2024-11-25
Estimated Completion Date: 2027-12
Participants
Target number of participants: 220
Treatments
Experimental: Internet-delivered exposure and response prevention (I-ERP)
A therapist-guided, internet-delivered exposure and response prevention (I-ERP) programme for children and adolescents with OCD and autism.
Active_comparator: Internet-delivered stress management (I-SM)
A therapist-guided, internet-delivered stress management (I-SM) programme for children and adolescents with OCD and autism.
Sponsors
Leads: Karolinska Institutet
Collaborators: Region Stockholm, Region Skane, Vastra Gotaland Region

This content was sourced from clinicaltrials.gov

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