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Scalp Hair Metabolomics as a Novel Biomarker of Poor Metabolic Health in Individuals With Severe Obesity

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The purpose of this research study is to investigate how body weight and weight-loss surgery affect the natural chemicals found in scalp hair over time. We will also find out how common and severe hair thinning/hair loss and muscle loss are in the first 6 months after bariatric surgery.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 21
Maximum Age: 70
Healthy Volunteers: t
View:

⁃ All subjects:

• Age 21-70 years

• Ability to provide informed consent

⁃ Healthy weight controls:

• BMI of 18.5-24.9 kg/m2

• No chronic disease

• No long-term medications

⁃ Severe obesity:

• BMI of \> 32.5 kg/m2

• Scheduled to undergo bariatric surgery

Locations
Other Locations
Singapore
Singapore General Hospital
RECRUITING
Singapore
Contact Information
Primary
Hong Chang Tan, MD PhD
tan.hong.chang@singhealth.com.sg
+65 63214658
Time Frame
Start Date: 2026-02-07
Estimated Completion Date: 2028-02
Participants
Target number of participants: 60
Treatments
Healthy controls
Healthy controls with normal weight
Severe obestiy
Participants with Severe obesity
Sponsors
Leads: Singapore General Hospital

This content was sourced from clinicaltrials.gov

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