Molecular Characterization for Understanding Biliary Atresia

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Although considered a rare disease, Biliary Atresia (BA) is the leading cause of neonatal cholestasis and liver transplantation in children. Little is known about the molecular mechanisms that drive BA. The purpose of this study is to collect the fluid samples, explanted liver tissue samples and dermal biopsy samples to enable investigators to perform the genetic and molecular analyses that might point to the gene(s) and cellular pathway involved in etiology of BA disease.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: t
View:

• confirmed diagnosis of biliary atresia in patients

• parents of BA patients

Locations
Other Locations
France
Hopital Necker enfants malades
RECRUITING
Paris
PRC Inserm
NOT_YET_RECRUITING
Paris
Time Frame
Start Date: 2021-02-07
Estimated Completion Date: 2032-02-07
Participants
Target number of participants: 100
Treatments
Experimental: BA patients and their parents
* Collection of blood samples from BA patients and their parents~* Collection of explanted liver tissue and skin biopsy of BA patients
Sponsors
Leads: Institut National de la Santé Et de la Recherche Médicale, France

This content was sourced from clinicaltrials.gov