The Acute and Chronic Impact of Blood Flow Restriction Resistance Training on Physical and Neuromuscular Function, Pain, and Quality of Life in Patients with Moderate/severe Hemophilia
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The main objectives of this study are to evaluate safety and chronic effects of a low-load resistance exercise intervention (elbow flexions and extensions, and knee extensions) with blood flow restriction in people with hemophilia on quality of life, pain, and on physical and neuromuscular function.
Eligibility
Participation Requirements
Sex: Male
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: f
View:
• diagnosis of hemophilia A or B and undergoing prophylaxis;
• willingness to exercise twice a week during the training program and to complete the pre- and post-program evaluations;
• approval by their hematologist to participate in the exercise program;
• age between 18 and 60 years;
• informed consent signed.
Locations
Other Locations
Spain
Facultat de Fisioteràpia
RECRUITING
Valencia
Contact Information
Primary
Sofía Pérez Alenda
sofia.perez-alenda@uv.es
+34655382100
Backup
Joaquín Calatayud
joaquin.calatayud@uv.es
+34625577509
Time Frame
Start Date: 2024-01-15
Estimated Completion Date: 2025-06-30
Participants
Target number of participants: 20
Treatments
Active_comparator: Control
The training program for the control group consists of a telerehabilitation with traditional moderate-to-high load (60%-80% 1RM) exercises (the same as the intervention group sans BFR), utilizing elastic bands. This program for the control group will be conducted in an in-home real-time audio and video style and supervised by a physiotherapist.
Experimental: BFRT
The BFR training program for the intervention group consists of elbow flexion and extension, and knee extension exercises performed with low load (elastic bands; equivalent to 30% 1RM) and concurrent BFR (upper limb 50% AOP; lower limb 60% AOP). Subjects will perform 4 sets (30, 15, 15 and 15 reps) of each exercise with 30 s rest between sets and 5-minute rest between exercises.
Related Therapeutic Areas
Sponsors
Leads: University of Valencia