Registering Genomics and Imaging of Tumors (ReGIT)

Status: Recruiting
Location: See location...
Intervention Type: Procedure, Drug
Study Type: Observational
SUMMARY

This study is investigating how brain tumors might mutate over time, and whether new brain imaging tools like MRI and PET can predict these mutations.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Subject is between 18 and 89 years of age.

• Subject has radiologically-diagnosed or suspected WHO Grade II-IV glioma based on physician review or conformance with published WHO criteria as evaluated by the PI\*.

• Subject is treatment-naïve with the exception of previous biopsy for the above condition.

• Subject is planning to undergo surgical resection and biopsy of their brain tumor.

• Subject has sufficient tissue so that the study team is able to acquire at least 2 biopsy samples during resection.

• Subject is able to read and write in English.

• Subject is able to lay supine for up to 80 minutes.

• Subject is able to hold still during MRI procedures.

• Subject or their LAR has signed the consent form for participation in the study.

Locations
United States
Indiana
Indiana University School of Medicine
RECRUITING
Indianapolis
Contact Information
Primary
Jason Parker, PhD
parkerjg@iu.edu
(317) 274-2072
Backup
Jason Parker, PhD
parkerjg@iu.edu
317-274-2072
Time Frame
Start Date: 2023-07-18
Estimated Completion Date: 2032-07-17
Participants
Target number of participants: 20
Treatments
Baseline Imaging and Biopsy
Subjects will receive a PET-CT with the radiopharmaceuticals FET and O-15 Water (under RDRC approval for basic research) prior to their standard of care neurosurgery via stereotactic core biopsy. Research samples will be collected for analysis intraoperatively.
Related Therapeutic Areas
Sponsors
Collaborators: Children's Hospital of Philadelphia
Leads: Indiana University

This content was sourced from clinicaltrials.gov