Neurocognition After Radiotherapy in Adult Brain and Base of Skull Tumors
Status: Recruiting
Location: See all (3) locations...
Intervention Type: Diagnostic test, Behavioral, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The goal of this multicenter prospective longitudinal study is to study the long-term impact of multimodal treatment (chemotherapy, radiotherapy and surgery) in adult brain and base of skull tumors on neurocognitive functioning. All included patients will complete a self-report inventory (subjective cognitive functioning, QoL, confounders), a cognitive test battery, an advanced MR at multiple timepoints. Moreover, toxicity will be scored according to the CTCAEv5.0 in these patients over time.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Adult patients (≥ 18 years at the time of diagnosis) with a primary brain or base of skull tumour, who are amenable for conventionally fractionated radiotherapy (photon or proton irradiation)
Locations
Other Locations
Belgium
University Hospitals Ghent
RECRUITING
Ghent
UZ Leuven
RECRUITING
Leuven
Gasthuis Zusters Antwerpen
RECRUITING
Wilrijk
Contact Information
Primary
Laurien De Roeck, MD
Laurien.deroeck@uzleuven.be
016 34 76 00
Backup
Maarten Lambrecht, MD PhD
Maarten.lambrecht@uzleuven.be
016 34 76 00
Time Frame
Start Date: 2023-02-08
Estimated Completion Date: 2027-02-01
Participants
Target number of participants: 120
Treatments
Other: Primary brain and skull-base tumors
Primary brain and skull-base tumors who are amenable for radiotherapy (photon or proton therapy) will all be examined with neurocognitive tests, questionnaires and advanced MR imaging
Related Therapeutic Areas
Sponsors
Collaborators: Gasthuis Zusters Antwerpen, University Hospital, Ghent
Leads: Universitaire Ziekenhuizen KU Leuven