Virtual-reality Exercises for Alleviating Attention Deficits in Patients with Acquired Brain Injury

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Stroke is the leading cause of long-term disability with an increasing incidence, especially in young adults. Among the cognitive difficulties following brain damage, deficits in attention are frequent and pervasive, affecting between 46% and 92% of stroke survivors. The current project targets patients with acquired brain injury, including stroke, traumatic brain injury, and brain tumor. The main objective of this study is to evaluate the use and the efficacy of a training program targeting attention and executive function difficulties, using gamified and digitized versions in virtual reality of standard cognitive exercises for patients with brain lesions.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Time from stroke onset \< 1 month

• Objective pathological performance on at least one standardized test or subtest on attention during standard neuropsychological evaluation

• Brain injury documented by routine neuroradiological examination (computed tomography or magnetic resonance imaging scan)

• Able to give informed consent as documented by signature

• Age \>= 18 years old

Locations
Other Locations
Switzerland
University of Lausanne Hospitals
RECRUITING
Lausanne
Contact Information
Primary
Sonia Crottaz-Herbette
sonia.crottaz-herbette@chuv.ch
+41213149348
Time Frame
Start Date: 2023-02-15
Estimated Completion Date: 2026-01-31
Participants
Target number of participants: 135
Treatments
Experimental: Rehabilitation intervention group
Each participant of the experimental group will undergo an initial cognitive screening (pre-training) and, in addition to their standard of care, they will have 20 additional sessions with the experimental rehabilitation program. Post-treatment cognitive screening will be completed at the end of the program, then 3-4 and 6-12 months later.
Active_comparator: Dose-match control group
Each participant of the experimental group will undergo an initial cognitive screening (pre-training) and, in addition to their standard of care, they will have 20 additional sessions of neuropsychological standard sessions. Post-treatment cognitive screening will be completed at the end of the program, then 3-4 and 6-12 months later.
No_intervention: Retrospective standard of care group
Each participant of the retrospective group will be included retrospectively if they were hospitalized in the study's sites between 2012 and 2022, and followed standard neuropsychological rehabilitation of attention.
Related Therapeutic Areas
Sponsors
Collaborators: University of Lausanne Hospitals
Leads: Mindmaze SA

This content was sourced from clinicaltrials.gov