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Self-administered Remote Neurological Examination Using Mobile Application in Patients With Brain Tumors

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Observational
SUMMARY

The goal of this observational study is to evaluate the feasibility and accuracy of a self-administered remote neurological examination using the Iskhaa mobile application in patients with brain tumors aged above 5 years who are able to follow app-based instructions. The main questions it aims to answer are: 1. Development of a mobile application equipped with symptom assessment and recording videos as patients perform specific neurological tasks. 2. Development and validation of the AI model to detect functional changes and predict subsequent neurological deterioration. Participants will: 1. Use the Iskhaa mobile application to perform guided self-neurological examinations following pre-recorded video instructions. 2. Complete EORTC QLQ-C30 and BN20 questionnaires for quality of life assessment. 3. Record and upload videos (e.g., speech, walking, limb movements) using their mobile camera for analysis. 4. In Phase 1 (onsite), 100 participants will use the app under supervision to ensure usability and accuracy. 5. In Phase 2 (offsite), 500 participants will use the app independently at home for monthly self-assessments, with reminders and follow-up support. 6. Continue routine clinic visits every 3-6 months and imaging every 6-12 months as per standard clinical care. The study will compare app-recorded data with physician assessments to determine agreement and validity of remote neurological monitoring using artificial intelligence analysis.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 5
Healthy Volunteers: f
View:

• Diagnosis of brain tumors (histopathology/ radiology).

• Age \> 5 years

• Patient or caregiver have access to an android smart phone and is able to install the mobile application.

• Expected survival more than 6 months during study accrual.

• Signing patient consent or parent consent/ child assent form (as appropriate).

Locations
Other Locations
India
Tata Memorial Centre
RECRUITING
Mumbai
Contact Information
Primary
Dr Archya Dasgupta, Radiation Oncology, MD
archya1010@gmail.com
8097081506
Time Frame
Start Date: 2026-02-20
Estimated Completion Date: 2027-11-05
Participants
Target number of participants: 600
Related Therapeutic Areas
Sponsors
Leads: Tata Memorial Centre
Collaborators: Bhabha Atomic Research Centre

This content was sourced from clinicaltrials.gov