Interaction Between Microbiome, Virome and Host Immunity Response in the Context of Protracted Bacterial Bronchitis
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
This project aims to assess the relationship between the microbiome and virome composition, the immune responses, and the respiratory health of children with protracted bacterial bronchitis (PBB). In addition, we aim to evaluate how the standard treatment with azithromycin interacts with the components of the microbiome, virome and immune biomarkers.
Eligibility
Participation Requirements
Sex: All
Maximum Age: 5
Healthy Volunteers: f
View:
• Children with PBB diagnosis according to case definition
• Consent form signed by parents or legal guardians
Locations
Other Locations
Belgium
Antwerp University Hospital
RECRUITING
Edegem
Contact Information
Primary
Kim Van Hoorenbeeck, Prof. dr.
kim.vanhoorenbeeck@uza.be
+3238213000
Backup
Irina Spacova, Prof. dr. ir.
irina.spacova@uantwerpen.be
+3232653289
Time Frame
Start Date: 2026-01-07
Estimated Completion Date: 2029-01
Participants
Target number of participants: 160
Treatments
Participants with Protracted bacterial bronchitis diagnostic
Children under five years old who attend pediatric outpatient visits or well-child visits at University Hospital Antwerp (UZA) and are diagnosed with Protracted bacterial bronchitis.
Related Therapeutic Areas
Sponsors
Leads: University Hospital, Antwerp