NUCLEuS: Evaluating DyNamic Myocardial Blood Flow QUantitation As a Cost Effective Care ModeL for DiabEtic Patients With Coronary Artery DiSease: A Randomized Controlled Trial
Status: Recruiting
Location: See location...
Intervention Type: Radiation
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This will be a prospective randomized clinical trial comprising of n=300 diabetic patients, randomized to either dynamic (n=150) or conventional MPI (n=150) strategy. Healthcare resources utilization of each patient will be tracked. Patients will be followed up for short term outcomes and for long term outcomes.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 21
Maximum Age: 90
Healthy Volunteers: f
View:
• Diabetic patients without known coronary artery disease referred for MPI
Locations
Other Locations
Singapore
National Heart Centre Singapore
RECRUITING
Singapore
Time Frame
Start Date: 2022-03-15
Estimated Completion Date: 2026-03
Participants
Target number of participants: 300
Treatments
Other: Dynamic myocardial perfusion imaging
Dynamic myocardial perfusion imaging is performed to obtain additional measurements of coronary blood flow, compared to conventional imaging.
Other: Conventional myocardial perfusion imaging
Conventional myocardial perfusion imaging which is based on standard routine clinical myocardial perfusion imaging.
Related Therapeutic Areas
Sponsors
Leads: National Heart Centre Singapore
Collaborators: National Medical Research Council (NMRC), Singapore