Comparison of the Efficacy Between Ultrasound-guided Dextrose Injection Versus Dextrose With Methylprednisolone Injection in Patients With Carpal Tunnel Syndrome: a Prospective, Randomized Double-blind Clinical Trial.
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
The goal of this prospective, randomized, double-blinded, head-to-head comparative study is to compare the efficacy of ultrasound-guided 4 ml 5% dextrose perineural injection versus 3 ml 5% dextrose with 1 ml 40 mg/ml methylprednisolone perineural injection in patients with carpal tunnel syndrome (CTS). The main questions it aims to answer are: Is there a difference in efficacy between interventions regarding 1. pain alleviation, 2. improvement in symptoms severity and functional status, 3. improvement in grip strength, 4. size of median nerve cross-sectional area, and 5. improvement in quality of life during the six-month post-intervention follow-up period?
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• age between 18 and 80 years,
• the diagnosis of idiopathic CTS.
Locations
Other Locations
Croatia
General and Veteran Hospital Croatian Pride Knin
RECRUITING
Knin
Contact Information
Primary
Igor Begović, MD
igorbegovic2@gmail.com
+385911748137
Backup
Nadica Laktašić Žerjavić, Prof,MD,PhD.
nadica_laktasic@yahoo.com
+385915606957
Time Frame
Start Date: 2023-09-13
Estimated Completion Date: 2026-08-30
Participants
Target number of participants: 70
Treatments
Active_comparator: 5% dextrose injection
Ultrasound-guided 4 ml single injection of 5% dextrose
Active_comparator: 5% dextrose injections with methylprednisolone acetate
Ultrasound-guided single injection of 3 ml 5% dextrose plus 1 ml 40 mg/ml methylprednisolone acetate
Related Therapeutic Areas
Sponsors
Collaborators: School of Public Health Andrija Štampar, Clinical Hospital Centre Zagreb
Leads: General and Veteran Hospital Croatian Pride Knin