Chagas Disease
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Chagas Disease Overview

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Learn About Chagas Disease

What is the definition of Chagas Disease?
Chagas disease is an infectious disease caused by the Trypanosoma cruzi parasite. The parasite is transmitted to animals and people by triatomine insects, also known as kissing bugs, which are mainly found in Latin America. If left untreated, Chagas disease is an inflammatory illness that can cause serious stomach and heart conditions.
What are the symptoms of Chagas Disease?
Chagas disease has acute (early) and chronic (late) phases. Symptoms of acute Chagas disease can start immediately after infection and last for weeks or months. Symptoms of acute Chagas disease may include fatigue, headache, fever, body aches, swollen glands, swelling at the site where infected, swollen eyelids, rash, loss of appetite, enlarged liver or spleen, and, in rare instances, severe inflammation of the brain, the lining of the brain, or the heart. After the acute phase, many individuals infected with Chagas disease may become asymptomatic. However, some individuals will progress to chronic Chagas disease. Symptoms of chronic Chagas disease may include abnormal heart rhythms, dilated heart, heart failure, cardiac arrest, dilated esophagus, difficulty swallowing, dilated colon, diarrhea, and abdominal pain.
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What are the current treatments for Chagas Disease?
Treatment for Chagas disease should begin early and may include benznidazole, nifurtimox, corticosteroids, dietary changes, pacemaker implantation, surgery, and heart transplantation.
Who are the top Chagas Disease Local Doctors?
Elite in Chagas Disease
Elite in Chagas Disease
Referral may be required
Sao Paulo, SP, BR 

Edecio Neto-Cunha practices practicing medicine in Sao Paulo, Brazil. Neto-Cunha is rated as an Elite expert by MediFind in the treatment of Chagas Disease. They are also highly rated in 2 other conditions, according to our data. Their clinical expertise encompasses Chagas Disease, Cardiomyopathy, HIV/AIDS, and COVID-19.

Elite in Chagas Disease
Elite in Chagas Disease
Referral may be required
Rua Dr Melo Alves, No 690, Apto 41, Cerqueira Cesar, 
Sao Paulo, SP, BR 

Edimar Bocchi practices practicing medicine in Sao Paulo, Brazil. Bocchi is rated as an Elite expert by MediFind in the treatment of Chagas Disease. They are also highly rated in 5 other conditions, according to our data. Their clinical expertise encompasses Chagas Disease, Heart Failure, Cardiomyopathy, Heart Transplant, and Heart Bypass Surgery.

 
 
 
 
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Elite in Chagas Disease
Elite in Chagas Disease
Referral may be required
100, Cp 28034, 
Madrid, MD, ES 

Rogelio Velez-Lopez practices practicing medicine in Madrid, Spain. Mr. Velez-Lopez is rated as an Elite expert by MediFind in the treatment of Chagas Disease. He is also highly rated in 14 other conditions, according to our data. His clinical expertise encompasses Chagas Disease, Togaviridae Disease, Rhabditida Infections, and Leishmaniasis.

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What are the latest Chagas Disease Clinical Trials?
A Randomized, Participant- and Investigator-blinded, Controlled, Parallel Group Study to Assess the Efficacy, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LXE408 in Participants With Chronic Chagas Disease Without Severe Organ Dysfunction.
A Randomized, Participant- and Investigator-blinded, Controlled, Parallel Group Study to Assess the Efficacy, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LXE408 in Participants With Chronic Chagas Disease Without Severe Organ Dysfunction.
Enrollment Status: Recruiting
Publish Date: August 19, 2026
Intervention Type: Drug
Study Phase: Phase 2

Summary: This study is to investigate the ability of LXE408 to clear or reduce the level of parasites in the blood of people with chronic Chagas disease. Participants must have chronic Chagas disease without severe organ dysfunction.

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Clinical and Functional Effects of Cardiac Contractility Modulation in Chagas Heart Disease: a Randomized Study - Contractility - FIX-Chagas
Clinical and Functional Effects of Cardiac Contractility Modulation in Chagas Heart Disease: a Randomized Study - Contractility - FIX-Chagas
Enrollment Status: Recruiting
Publish Date: July 08, 2026
Intervention Type: Device
Study Phase: Not Applicable

Summary: Chagas disease is an endemic problem in Latin America, where millions of people are chronically infected with T. cruzi. Recently, it was assumed to have clinical and epidemiological relevance in several other countries due to migratory and globalizing social factors. CCC occurs in 30-50% of infected individuals, causing considerable morbidity/mortality rates. Heart failure is the most prevalent mo...

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