Chronic B-Cell Leukemia (CBCL)
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Learn About Chronic B-Cell Leukemia (CBCL)

View Main Condition: Leukemia

What is the definition of Chronic B-Cell Leukemia (CBCL)?
Chronic B cell leukemia is a type of chronic lymphocytic leukemia (CLL), or cancer of the blood and bone marrow that mainly affects adults. In chronic B cell leukemia, the bone marrow produces too many B lymphocytes, which are white blood cells that fight infection. Chronic B cell leukemia represents 95% of all chronic lymphocytic leukemias.
What are the symptoms of Chronic B-Cell Leukemia (CBCL)?
Individuals with early chronic B cell leukemia may not have any symptoms. Symptoms of intermediate and advanced stage chronic B cell leukemia may include painless, enlarged lymph nodes; fatigue; fever; pain in the upper left region of the abdomen; enlarged spleen; easy bruising or bleeding; pinpoint, dark red spots under the skin (petechiae); night sweats; weight loss; and frequent infections.
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What are the current treatments for Chronic B-Cell Leukemia (CBCL)?
Treatment for chronic B cell leukemia depends on the stage. Early stage chronic B cell leukemia may not need treatment and may involve watchful waiting. Treatment for intermediate and advanced stages chronic B cell leukemia may include targeted therapy, chemotherapy, radiation therapy, immunotherapy, and bone marrow or peripheral stem cell transplant.
Who are the top Chronic B-Cell Leukemia (CBCL) Local Doctors?
Elite in Chronic B-Cell Leukemia (CBCL)
Hematology Oncology | Hematology | Oncology
Elite in Chronic B-Cell Leukemia (CBCL)
Hematology Oncology | Hematology | Oncology

Northwell Health Center For Advanced Medicine, RJ Zuckerberg Cancer Center

450 Lakeville Road, Entrance B, 
Lake Success, NY 
Languages Spoken:
English

The Chronic Lymphocytic Leukemia (CLL) Research and Treatment Program has become a landmark for CLL patients worldwide. Dr. Kanti Rai has been involved in diagnosing and treating CLL for almost 40 years and the staging system that bears his name came out of his early breakthrough research. His particular areas of interest are: natural history of CLL, improving prognostic features of this disease and developing newer strategies of therapy which are hypothesis-driven. Dr. Rai is an active member of the International Workshop on CLL (iwCLL) and Dr. Keating s Global CLL Foundation. He is an active member of the American Society of Clinical Oncology (ASCO), American Association for Cancer Research (AACR) and the American Society of Hematology (ASH). In 2006, Dr. Rai served as the President of ASH. He was the recipient of ASCO s David Karnofsky Memorial Award in 2012. In 2013, Dr. Rai was honored with the iwCLL David Galton award. In 2014 he was presented with ASH s Wallace H. Coulter Lifetime Achievement Award. Dr. Rai is the Joel Finkelstein Cancer Foundation Professor of Medicine, and Professor of Molecular Medicine at the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell School of Medicine and Professor of Medicine at the Feinstein Institute for Medical Research, Manhasset, NY. Dr. Rai is rated as an Elite provider by MediFind in the treatment of Chronic B-Cell Leukemia (CBCL). He is also highly rated in 7 other conditions, according to our data. His clinical expertise encompasses Chronic B-Cell Leukemia (CBCL), Chronic Lymphocytic Leukemia (CLL), Leukemia, and Richter Syndrome. Dr. Rai is board certified in American Board Of Pediatrics.

Elite in Chronic B-Cell Leukemia (CBCL)
Hematology Oncology | Hematology | Oncology
Elite in Chronic B-Cell Leukemia (CBCL)
Hematology Oncology | Hematology | Oncology

Cleveland Clinic Main Campus

10201 Carnegie Avenue, 
Cleveland, OH 
Experience:
30+ years
Languages Spoken:
English
Offers Telehealth

Brian Hill is a Hematologist Oncology specialist and a Hematologist practicing medicine in Cleveland, Ohio. He has been practicing medicine for over 30 years. Dr. Hill is rated as an Elite provider by MediFind in the treatment of Chronic B-Cell Leukemia (CBCL). He is also highly rated in 30 other conditions, according to our data. His clinical expertise encompasses Non-Hodgkin Lymphoma, B-Cell Lymphoma, Diffuse Large B-Cell Lymphoma (DLBCL), Bone Marrow Transplant, and Bone Marrow Aspiration.

 
 
 
 
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Elite in Chronic B-Cell Leukemia (CBCL)
Elite in Chronic B-Cell Leukemia (CBCL)

Northwell Health Center For Advanced Medicine, RJ Zuckerberg Cancer Center

450 Lakeville Road, Entrance B, 
Lake Success, NY 
Languages Spoken:
English, Spanish
Offers Telehealth

Jonathan Kolitz, MD, FACP, is Professor of Medicine at the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell. An expert in malignant hematology, he is the System Head for Malignant Hematology for the Northwell Health Cancer Institute where he guides the clinical care and research activities of faculty and fellows. Board certified in Internal Medicine, Hematology and Medical Oncology, Dr. Kolitz has been a member of the Leukemia Core Committee of the CALGB/Alliance since 1993. He has focused on the development, conduct and publication of innovative clinical trials for the treatment of hematologic malignancies, especially acute leukemia. He has been principal investigator for numerous novel drug trials and has been involved in multiple national and international collaborations, leading to over 200 publications. As an attending physician at the Monter Cancer Center, Dr. Kolitz focuses on providing compassionate, personalized, evidence-based care. Dr. Kolitz earned his medical degree from the Yale University School of Medicine. He trained in Internal Medicine at North Shore University Hospital and Hematology and Medical Oncology at Memorial Sloan-Kettering Cancer Center. Dr. Kolitz is an active member of the American Society of Hematology, American Society of Clinical Oncology and the American College of Physicians. Dr. Kolitz is rated as an Elite provider by MediFind in the treatment of Chronic B-Cell Leukemia (CBCL). He is also highly rated in 46 other conditions, according to our data. His clinical expertise encompasses Leukemia, Chronic B-Cell Leukemia (CBCL), Acute Myeloid Leukemia (AML), Chronic Lymphocytic Leukemia (CLL), and Bone Marrow Aspiration. Dr. Kolitz is board certified in American Board Of Internal Medicine, American Board Of Internal Medicine/Hematology, and American Board Of Internal Medicine/Medical Oncology.

What are the latest Chronic B-Cell Leukemia (CBCL) Clinical Trials?
An Open-Label, Single-Arm, Phase 1/2 Study Evaluating the Safety and Efficacy of Ponatinib for the Treatment of Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors in Pediatric Participants

Summary: The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, and efficacy of ponatinib in children aged 1 to \< 18 years with advanced leukemias, lymphomas, and solid tumors.

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Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax

Background: Bruton s tyrosine kinase inhibitors (BTKi) are used to treat a form of leukemia. But taking BTKi can also increase a person s risk of developing an abnormal heart rhythm. This can cause sudden death. In this natural history study, researchers want to learn how BTKi affects the heart.