ESPEN-EASO Sarcopenic Obesity (OS) Diagnostic Criteria Application in a COPD Cohort and OS Correlation to Diaphragmatic Thickness and Mobility for Determination of Tailored Pulmonary Rehabilitation Program: an Observational Study

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The goal of this observational study is to the purpose is to apply of ESPEN/EASO criteria for the diagnosis of sarcopenic obesity and calculation of OS prevalence in a sample of COPD patients. In addition, this study want to evaluate the impact of sarcopenic obesity on the respiratory function of COPD patients and the degree of severity of respiratory disease, assessed by spirometric examination; diaphragm thickness and excursion, by ultrasonographic study; performance, assessed by six-minute walk test (6-MWT); quality of life and degree of dyspnea (mMRC, Barthel dyspnea, S. George Respiratory Questionnaire); compliance and outcomes at the end of the respiratory rehabilitation course. Comparison with normal-weight patients with and without sarcopenia will help to better understand the clinical impact of sarcopenic obesity in this category of patients.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Maximum Age: 100
Healthy Volunteers: f
View:

• Patients aged \> 40 years of either sex;

• BMI \>18.5

• COPD diagnosis according to the GOLD \[2021 Global initiative for chronic obstructive lung disease\] classification in the stable stage;

• Signing of informed consent after receiving all information about the study.

Locations
Other Locations
Italy
IRCCS San Raffaele
RECRUITING
Roma
Contact Information
Primary
Lucia Gatta, PhD
lucia.gatta@sanraffaele.it
0039 0652253440
Backup
Franco Pasqua, MD
franco.pasqua@sanraffaele.it
0039 0652258336
Time Frame
Start Date: 2024-06-01
Estimated Completion Date: 2025-06-30
Participants
Target number of participants: 236
Treatments
Normal weight
18.5\< BMI \> 24.99
Overweight
25\< BMI \> 29.99
Obese
BMI \> 30
Sponsors
Leads: IRCCS San Raffaele Roma

This content was sourced from clinicaltrials.gov