The Use of Entropy to Assess Sleep Disordered Breathing in Chronic Respiratory Disease

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Research is being conducted into chronic respiratory diseases, including chronic obstructive pulmonary disease (COPD), asthma, interstitial lung disease, and bronchiectasis. The investigation specifically focuses on sleep-disordered breathing (SDB) in individuals with chronic respiratory disease. SDB encompasses a range of conditions, the most common of which is obstructive sleep apnoea. In obstructive sleep apnoea, periodic pauses in breathing (apnoea) lead to reduced blood oxygen levels. To detect these events, patients typically undergo sleep studies that involve monitoring oxygen saturation, heart rate, and respiratory patterns during sleep. When chronic respiratory disease and SDB coexist, breathing disturbances during sleep may be exacerbated. To identify SDB, sleep studies are commonly used to assess oxygen levels, heart rate, and breathing patterns. The objective of this research is to identify differences between patients with chronic respiratory diseases who have SDB and those who do not. This will be achieved by analysing sleep study data using a novel analytical approach. The aim is to determine whether this method can yield more detailed insights into the underlying pathophysiology of these conditions.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• All adult patients (≥ 18years) with chronic respiratory disease with/without SDB.

• patients who have had previously negative studies as a control group.

• Subject is able to read, understand, and sign the informed consent form.

• Willing to sleep with portable monitoring devices.

Locations
Other Locations
United Kingdom
Royal Free hospital
RECRUITING
London
Contact Information
Primary
Nawal Alotaibi
n.alotaibi@ucl.ac.uk
02080168375
Time Frame
Start Date: 2025-04-30
Estimated Completion Date: 2026-09-30
Participants
Target number of participants: 120
Sponsors
Collaborators: Royal Free Hospital NHS Foundation Trust
Leads: University College, London

This content was sourced from clinicaltrials.gov