Study of Analgesic Action of Pregabalin, Duloxetine and Tramadol in Patients With Different Neuropathic Pain Phenotypes. Clinical Study

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Observational
SUMMARY

Chronic pain is the most frequent cause from which millions of patients suffer worldwide, which makes them unable to work but also greatly affects their quality of life. Chronic pain is a condition in itself. Neuropathic pain is a consequence of damage or disease of the peripheral or central nervous system and presents a heterogeneous clinical profile. A large number of pharmaceutical and non-pharmacological agents, as well as various complementary therapies, have been used in the treatment of neuropathic pain. However, their effectiveness is considered moderate and limited and is under investigation because a significant proportion of patients do not respond satisfactorily to treatment. Purpose: The purpose of the study is to investigate the effectiveness of analgesics in the different phenotypes of neuropathic pain.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• neuropathic pain

Locations
Other Locations
Greece
AHEPA University General of Thessaloniki, Chronic Pain Unit
RECRUITING
Thessaloniki
Contact Information
Primary
Ioannis Dalakakis, MD, MSc
idalakakis@gmail.com
+306948536554
Backup
Ekaterini Amaniti, MD, PhD
amanitik@gmail.com
+306937248827
Time Frame
Start Date: 2018-03-05
Estimated Completion Date: 2024-09-07
Participants
Target number of participants: 100
Treatments
Neuropathic pain patients
Patients were randomized to pregabalin (group A) and duloxetine (group B). Those patients who did not have a 50% reduction in pain levels received duloxetine (group A) and pregabalin (group B). Then, those patients who did not have a 50% reduction in pain levels received tramadol.
Related Therapeutic Areas
Sponsors
Leads: Aristotle University Of Thessaloniki

This content was sourced from clinicaltrials.gov