Investigation of the Efficacy of Transcranial Magnetic Stimulation in Patients Developing Complex Regional Pain Syndrome Type 1 in the Upper Extremity During the Subacute-Chronic Period After Ischemic Stroke
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The aim of our study is to investigate transcranial magnetic stimulation (TMS) as a treatment option in Complex Regional Pain Syndrome, disseminate it to a broader patient population, and simultaneously demonstrate its applicability in the treatment of complex regional pain syndrome using a novel frequency matching.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• Clinical diagnosis of Complex Regional Pain Syndrome Diagnosis of ischemic stroke
Locations
Other Locations
Turkey
Ankara Bilkent City Hospital Physical Therapy and Rehabilitation Hospital
RECRUITING
Ankara
Contact Information
Primary
Hüma Bölük Şenlikçi Associate Professor
humaboluk@gmail.com
+905370630777
Backup
Özlem Yücealp Ali Medical Doctor
ozlem.yucealp@gmail.com
+905318491996
Time Frame
Start Date: 2023-11-15
Estimated Completion Date: 2024-12-15
Participants
Target number of participants: 45
Treatments
Active_comparator: active transcranial magnetic stimulation in stroke patients with complex regional pain syndrome
The intermittent theta-burst stimulation (iTBS) intensity for patients, applied under doctor supervision for a total of 5 days over one week (from Monday to Friday), will be set at 70% of the resting motor threshold. Stimulation will consist of bursts at a frequency of 50 Hz, with 3 bursts every 10 seconds, each burst lasting 2 seconds, totaling 600 bursts. Subsequently, the resting motor threshold will be adjusted to 80%, and a total of 2000 bursts will be delivered at a frequency of 10 Hz, repeated every 30 seconds, each lasting 10 seconds.
Sham_comparator: sham transcranial magnetic stimulation in stroke patients with complex regional pain syndrome
Similar protocol will be applied and sham transcranial magnetic stimulation treatment will be given with a sham coil to the sham group.
Placebo_comparator: conventional rehabilitation program in stroke patients with complex regional pain syndrome
Only a conventional rehabilitation program consisting of discontinuous ultrasound, transcutaneous electrical nerve stimulation (TENS), and contrast bath, formed by 5 sessions, will be applied to this group.
Related Therapeutic Areas
Sponsors
Leads: Ankara City Hospital Bilkent