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Exploring the Clinical Benefits of Precision Vibration on Neuromuscular Induction, Proprioceptive Gain, Functional Enhancement, and Pain Relief in Older Adults and and Stroke Survivors

Status: Recruiting
Location: See location...
Intervention Type: Other, Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

To address muscle weakness, sensory degradation, functional decline, and pain caused by geriatric syndromes in older adults and stroke survivors, this project proposes a series of studies aimed at improving neuromuscular performance, muscle strength, proprioceptive gain, functional outcomes, and pain relief through the use of a precise vibration system. In the first phase, a vibration exercise system will be implemented to recruit frail older adults and older adults with stroke for clinical trials. The goal is to verify the benefits of vibration intervention on limb muscle strength, proprioception, and movement function. In the third phase, quantitative pain assessments and related scales will be used to evaluate chronic pain thresholds and affected regions in older adults and stroke survivors, and to validate the effectiveness of vibration intervention in alleviating their pain.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 95
Healthy Volunteers: f
View:

⁃ Older Adults:

• Meet two or more criteria of the Study of Osteoporotic Fractures (SOF) frailty index

• Willing to participate in the study and comply with all study procedures

• Able to wear and safely use the vibration device

• Normal cognitive function (Mini-Mental State Examination \[MMSE\] score ≥ 23)

• Presence of knee joint pain in the lower limbs

⁃ Stroke Survivors:

• Clinical diagnosis of ischemic or hemorrhagic stroke confirmed by a physician

• Clinically stable stroke condition (i.e., not in an acute or unstable phase)

• Brunnstrom stage ≥ III for the affected limb

• Cognitive ability sufficient to follow study procedures (MMSE score ≥ 23)

• Modified Ashworth Scale (MAS) score \< 3 for the paretic limb

• Able to sit safely and participate in vibration or rehabilitation sessions for up to 60 minutes per visit

• Willing and able to comply with all study procedures and provide written informed consent

Locations
Other Locations
Taiwan
National Center for Geriatrics and Welfare Research, National Health Research Institutes
RECRUITING
Taipei
Contact Information
Primary
Po-Jung Chen, Ph.D.
pojungchen@nhri.edu.tw
+886-5-632-5080
Time Frame
Start Date: 2024-09-18
Estimated Completion Date: 2027-12-31
Participants
Target number of participants: 80
Treatments
Active_comparator: Older Adults (Conventional Rehabilitation)
Older adults without stroke receive 60 minutes of conventional rehabilitation per session, including individualized strength, mobility, and balance training. Therapy duration is matched to the intervention group. Outcomes assessor is blinded.
Experimental: Older Adults (Vibration Therapy on Upper or Lower Limb)
Older adults without stroke receive 20 minutes of precision vibration therapy (applied to the upper or lower limb according to primary deficit) followed by 40 minutes of conventional rehabilitation per session. The total session time equals 60 minutes. Outcomes assessor is blinded.
Active_comparator: Stroke Survivors (Conventional Rehabilitation)
Stroke survivors (≥18 years) receive 60 minutes of conventional rehabilitation per session, including task-specific training, strengthening, and mobility exercises. Therapy duration is matched to the intervention group. Outcomes assessor is blinded.
Experimental: Stroke Survivors (Vibration Therapy on Upper or Lower Limb)
Stroke survivors receive 20 minutes of precision vibration therapy applied to the affected upper or lower limb followed by 40 minutes of conventional rehabilitation per session (total 60 minutes). Intervention aims to improve muscle strength, proprioception, and functional outcomes. Outcomes assessor is blinded.
Related Therapeutic Areas
Sponsors
Leads: National Health Research Institutes, Taiwan

This content was sourced from clinicaltrials.gov