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Pain Reprocessing Therapy for Chronic Low Back Pain: A Pilot Randomized Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Behavioral, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to learn whether Pain Reprocessing Therapy (PRT) is a feasible and acceptable treatment to complete for working-age adults (ages 18-65) with chronic low back pain. The main questions it aims to answer are: Is PRT acceptable and feasible for people with chronic low back pain to complete? Does PRT help reduce pain intensity and interference, while improving functional outcomes in people with chronic low back pain? Researchers will compare PRT to a Monitoring and Education Program to see whether participants who receive PRT experience greater improvements in pain, daily functioning, and well-being. Participants will: * Be randomly assigned to the PRT group or the Monitoring and Education group * Participate in 8 intervention sessions over an 8-week period * Wear an activity monitor for 8 weeks * Attend a follow-up assessment after completing the intervention and another assessment 3 months later Please note that ClinicalTrials.gov will be used solely as a public study registry and not as a participant recruitment tool. The study team will not recruit participants or accept self-referrals through ClinicalTrials.gov. All participant recruitment will occur only through the Research Ethics Board (REB) approved recruitment methods.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:

• Working age adults (18-65)

• Male or Female at birth

• Persisting back pain for at least 3 months occurring at least half of the days in the past 6 months

• Pain score of at least 4/10 (on a 10-point rating scale)

• Ability to speak and understand English in order to follow study procedures and engage in study interventions.

Locations
Other Locations
Canada
Toronto Rehabilitation Institute - University Centre
RECRUITING
Toronto
Contact Information
Primary
Mariam Hasan
Pain@uhn.ca
+1 416-597-3422
Backup
Andrea Furlan, MD
Andrea.Furlan@uhn.ca
+1 416-597-3422
Time Frame
Start Date: 2026-07-15
Estimated Completion Date: 2027-06
Participants
Target number of participants: 30
Treatments
Active_comparator: Control Arm - Monitoring and Education
Participants will receive an 8-week monitoring and education program consisting of weekly sessions focused on pain education, symptom and activity level monitoring, and self-management strategies for chronic low back pain.
Experimental: Treatment Arm - Pain Reprocessing Therapy
Participants will receive an 8-week Pain Reprocessing Therapy (PRT) program consisting of weekly therapist-led one-on-one sessions designed to reduce pain.
Related Therapeutic Areas
Sponsors
Collaborators: Workplace Safety and Insurance Board
Leads: University Health Network, Toronto

This content was sourced from clinicaltrials.gov