Evaluation of Protein Distribution Optimization With Exercise Regimen on Nutritional Status, Body Composition and Functional Status in Patients Awaiting Liver Transplantation: The POWER-LT Randomized Clinical Trial
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study aims to evaluate the effects of a diet with even protein distribution plus exercise (Group A) versus a diet with skewed protein distribution plus exercise (Group B) versus standard dietary and physical activity advice (Group C) on nutritional status, body composition and functional status in patients awaiting liver transplantation.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:
• End-stage liver disease, diagnosed by transient elastography (FibroScan) or imaging-based evaluation with compatible clinical picture
• Referred for liver transplantation and evaluated to have a high likelihood of being listed, according to primary hepatologist assessment, or already listed for liver transplantation
• No prior formal dietary advice
Locations
Other Locations
Greece
Agricultural University of Athens
RECRUITING
Athens
Laiko General Hospital of Athens
RECRUITING
Athens
Contact Information
Primary
Kalliopi Anna Poulia
lpoulia@aua.gr
+30 2105294668
Backup
Evangelos Cholongitas
echolog@med.uoa.gr
+30 2132061643
Time Frame
Start Date: 2026-01-08
Estimated Completion Date: 2029-07
Participants
Target number of participants: 90
Treatments
Experimental: Diet with even protein distribution plus exercise program
Experimental: Diet with skewed protein distribution plus exercise program
Active_comparator: Standard dietary and physical activity advice
Related Therapeutic Areas
Sponsors
Collaborators: Laikο General Hospital, Athens
Leads: Kalliopi Anna Poulia