A Multicenter, Double-blind, Randomized, Placebo-controlled Study of the Efficacy and Safety of Ingavirin®, Syrup, 30 mg/5 ml, in Children Aged 6 Months to 2 Years With Influenza and Other Acute Respiratory Viral Infections Against Standard Therapy

Who is this study for? Children with influenza and other acute respiratory viral infections
What treatments are being studied? Ingavirin®
Status: Completed
Location: See all (8) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

The study is planned to evaluate the therapeutic efficacy and safety of Ingavirin®, syrup, 30 mg/5 ml, in the treatment of influenza or other acute respiratory infections in children from 6 months to 2 years compared with placebo.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 6 months
Maximum Age: 2
Healthy Volunteers: f
View:

• Patient's parent/adoptive parent's informed consent form voluntarily signed by the patient's parent/adoptive parent;

• Boys and girls aged 6 months - 2 years 11 months 14 days, inclusive, with the following clinical signs of acute respiratory infections/flu: body temperature above 38.0 °C but not higher than 39.0 °C (without taking antipyretics within the last 8 h) at the time of screening/randomization; at least one of the respiratory manifestations of acute respiratory infection/influenza (cough, runny nose/ stuffy nose) of at least 2 points on a 4-point scale; decrease in the child's daytime activity and change in nighttime sleep, as compared with the state before the illness;

• There were no indications for hospitalization at the time of inclusion in the study;

• Duration of illness from manifestation of symptoms to inclusion in the study not more than 48 hours.

Locations
Other Locations
Russian Federation
Federal Research and Clinical Center of Physical and Chemical Medicine of the Federal Medical and Biological Agency
Odintsovo
City Pediatric Outpatient Clinic number 5
Perm
Professors' Clinic LLC.
Perm
City Polyclinic No. 45 of Nevsky District
Saint Petersburg
PiterKlinika LLC
Saint Petersburg
St. Petersburg State Budgetary Healthcare Institution Children's City Polyclinic No. 44
Saint Petersburg
Uromed LLC
Smolensk
Bashkir State Medical University
Ufa
Time Frame
Start Date: 2021-09-23
Completion Date: 2022-07-15
Participants
Target number of participants: 240
Treatments
Experimental: Ingavirin®, syrup, 30 mg/5 ml
Ingavirin®, syrup, 30 mg/5 ml will be administered on top of standard therapy
Placebo_comparator: Placebo
Placebo will be administered on top of standard therapy
Related Therapeutic Areas
Sponsors
Leads: Valenta Pharm JSC

This content was sourced from clinicaltrials.gov