Follow-up During the Peripubertal Period of Preterm Children (Under 35 Weeks of Amenorrhea) Included in the EPIPOD Protocol : Evaluation of Insulin Resistance

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Prematurity is associated with an increased risk of developing cardiovascular and metabolic disturbances in adulthood. It has been demonstrated that the body composition of children born prematurely is different from that of children born under term with a deficit in fat free mass. It can thus be wondered if this excessive adiposity does or does not predict the risk of insulin resistance in adulthood. Children born prematurely, with a body composition measurement performed at discharge from neonatal hospitalization as part of the EPIPOD protocol, and now aged between 8 and 14 years, will be included in the INFANTPOD protocol. Analysis of body composition, insulin resistance, renal function, pulse wave velocity, eating behaviour and of physical activity will be performed.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 8
Maximum Age: 14
Healthy Volunteers: f
View:

• Children hospitalised at the Nantes University Hospital in the neonatal period

• With a body composition measurement performed at discharge from neonatal hospitalization as part of the EPIPOD protocol

• Born prematurely (under 35 weeks of amenorrhea)

• Included in the Lift cohort with follow-up up to 7 years

• Aged between 8 and 14 years at inclusion

Locations
Other Locations
France
Nantes University Hospital
RECRUITING
Nantes
Contact Information
Primary
Anne FRONDAS, Doctor
anne.frondas@chu-nantes.fr
+33 2 40 08 34 83
Time Frame
Start Date: 2022-02-02
Estimated Completion Date: 2028-02-02
Participants
Target number of participants: 114
Treatments
Experimental: Children born prematurely included in the EPIPOD protocol and now in the peripubertal period
At inclusion in the INFANTPOD study :~* Blood and urinary samples collection for evaluation of insulin resistance and of renal function analysis.~* Assessment of body composition by a commercialized device called BOP-POD and by impedancemetry~* Assessment of pulse wave by a commercialized device called popmetre~* Questionnaires for analysis of eating behaviour~* Assessment of physical activity by a commercialized device called accelerometer and by questionnaire.
Related Therapeutic Areas
Sponsors
Leads: Nantes University Hospital

This content was sourced from clinicaltrials.gov