Crouzon SyndromeSymptoms, Doctors, Treatments, Advances & More
Crouzon Syndrome Overview
Learn About Crouzon Syndrome
Crouzon syndrome is a genetic disorder characterized by the premature fusion of certain skull bones (craniosynostosis). This early fusion prevents the skull from growing normally and affects the shape of the head and face.
Mutations in the FGFR2 gene cause Crouzon syndrome. This gene provides instructions for making a protein called fibroblast growth factor receptor 2. Among its multiple functions, this protein signals immature cells to become bone cells during embryonic development. Mutations in the FGFR2 gene are thought to result in production of an FGFR2 protein with overactive signaling, which causes the bones of the skull to fuse prematurely.
Crouzon syndrome is seen in about 16 per million newborns. It is the most common craniosynostosis syndrome.
This condition is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder.
Penn Plastic Surgery Perelman
Scott Bartlett is a Plastic Surgeon practicing medicine in Philadelphia, Pennsylvania. Dr. Bartlett is rated as an Elite provider by MediFind in the treatment of Crouzon Syndrome. He is also highly rated in 29 other conditions, according to our data. His clinical expertise encompasses Craniosynostosis, Pfeiffer Syndrome, Apert Syndrome, Osteotomy, and Bone Graft. Dr. Bartlett is board certified in Plastic Surgery, 1987. Dr. Bartlett is currently accepting new patients.
Penn Plastic Surgery University City
Jordan Swanson is a General Surgeon and a Plastic Surgeon practicing medicine in Philadelphia, Pennsylvania. He has been practicing medicine for over 18 years. Dr. Swanson is rated as an Elite provider by MediFind in the treatment of Crouzon Syndrome. He is also highly rated in 30 other conditions, according to our data. His clinical expertise encompasses Craniosynostosis, Plagiocephaly, Crouzon Syndrome, Osteotomy, and Bone Graft. Dr. Swanson is board certified in Plastic Surgery, 2018. Dr. Swanson is currently accepting new patients.
Office
Jesse Taylor is a Plastic Surgeon practicing medicine in Philadelphia, Pennsylvania. Dr. Taylor is rated as an Elite provider by MediFind in the treatment of Crouzon Syndrome. He is also highly rated in 40 other conditions, according to our data. His clinical expertise encompasses Craniosynostosis, Crouzon Syndrome, Treacher Collins Syndrome, Osteotomy, and Glossectomy.
Summary: This clinical study aims to evaluate the effectiveness of patient-specific 3D-printed titanium facial implants in the reconstruction and aesthetic correction of facial defects. The study will include patients presenting with congenital, traumatic, or post-surgical facial deformities requiring reconstructive intervention. Eligible participants will undergo preoperative clinical assessment and radio...
Summary: The aim of this study is to evaluate the comparison of therapeutic potential of curcumin preconditioned adipose derived stem cells (ASCs) enrichment fat grafting, naïve ASCs enrichment fat grafting and conventional fat grafting to correct facial contour deformities that cause aesthetic complications in patients.
Published Date: January 01, 2020
Published By: National Institutes of Health