Association Between Local Cerebral Oxygen Saturation Monitoring and Postoperative Delirium in Carotid Endarterectomy:A Prospective Cohort Study

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Observational
SUMMARY

Postoperative delirium (POD) is a common perioperative complication, which can lead to adverse outcomes. Patients undergoing carotid endarterectomy (CEA) were elderly, complicated with vascular risk factors, cognitive dysfunction, some also had a history of stroke, and the circulation fluctuated greatly during the operation, often resulting in hypoperfusion of cerebral tissue and hypoxia. Therefore, they're the high-risk group of POD. Near-infrared Spectroscopy (NIRS) can continuously and noninvasively monitor local cerebral oxygen saturation (SctO2) to identify the mismatch of oxygen supply and demand in brain tissue. However, for CEA patients, the association between intraoperative SctO2 changes and POD remains unclear. This study intends to explore the association between them and determine the SctO2 threshold for predicting POD. We will monitor SctO2 intraoperatively, follow up and collect data postoperatively.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• Scheduled carotid endarterectomy; Signed informed consent.

Locations
Other Locations
China
Beijing Tian Tan Hospital, Capital Medical University
RECRUITING
Beijing
Contact Information
Primary
Yuming MD Peng, Ph.D
florapym766@163.com
8610-59976658
Time Frame
Start Date: 2022-02-14
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 140
Treatments
Group 1
Group 2
Related Therapeutic Areas
Sponsors
Leads: Beijing Tiantan Hospital

This content was sourced from clinicaltrials.gov