Intraoperative Diagnosis of Neurocognitive Complications Via Electroencephalographic (IDEA Network)

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Observational
SUMMARY

Postoperative neurocognitive disorders (PND) are serious and common complications after surgery, especially in elderly patients. These disorders can affect cognitive functions for years, deteriorating quality of life and increasing hospital stays and medical costs. Diagnosing PND is challenging due to their varied manifestations, such as memory and attention problems, and the lack of standardized criteria and biomarkers. One well-studied form of PND is postoperative delirium (POD). According to the ICD-10, POD is an organic cerebral syndrome characterized by disturbances in consciousness, attention, perception, and other cognitive functions. Researchers suggest that POD development involves a combination of predisposing and precipitating factors. Electroencephalography (EEG) has been used in anesthesiology to assess anesthesia depth and intraoperative awareness. Modern EEG analysis methods, like spectral analysis, offer new ways to evaluate patients' neurophysiological states. Studies show that EEG monitoring can predict complications such as intraoperative stroke and delirium, particularly in cardiothoracic and neurosurgical operations. The relationship between EEG patterns and POD is not well understood. Specific EEG patterns may indicate the risk of POD, aiding in the identification of risk factors and prevention methods. This could help anesthesiologists and surgeons optimize their approaches, reducing the risk of cognitive complications.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age ≥ 18 years

• Scheduled non-cardiac surgery of intermediate or high risk

• General anesthesia using inhalational anesthetics

• Informed consent from the patient to participate in the study

Locations
Other Locations
Russian Federation
City clinical hospital named after SS Yudin
RECRUITING
Moscow
Contact Information
Primary
Valery Likhvantsev, PhD
lik0704@gmail.com
89036235982
Backup
Levan Berikashvili, PhD
levan.berikashvili@mail.ru
89263308968
Time Frame
Start Date: 2024-09-25
Estimated Completion Date: 2027-08-20
Participants
Target number of participants: 265
Treatments
Non-cardiac surgery
Patients scheduled for non-cardiac surgery of intermediate to high risk
Related Therapeutic Areas
Sponsors
Leads: Federal Research and Clinical Centre of Intensive Care Medicine and Rehabilitology

This content was sourced from clinicaltrials.gov