Cognitive Decline and Underlying Mechanisms in Asymptomatic Intracranial Artery Stenosis Patients: A Cohort Study
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Observational
SUMMARY
The purpose of this study is to explore the mechanism of cognitive impairment in patients with asymptomatic intracranial atherosclerotic stenosis(ICAS),and to examine the natural history and the pathogenesis of asymptomatic ICAS.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• Patients with intracranial stenosis which was defined as stenosis of 50% or more in Intracranial segment of internal carotid artery(C6-C7) and middle cerebral artery (M1).
• The degree of stenosis was measured by transcranial doppler, computed magnetic resonance angiography (MRA),tomography angiography (CTA) and digital subtraction angiography (DSA).
Locations
Other Locations
China
Anhui Medical University
RECRUITING
Hefei
Contact Information
Primary
Kai Wang, PhD
wangkai1964@126.com
+86-0551-62922263
Backup
Qiang Wei, PhD
qiangwei_914@126.com
+86-62922418
Time Frame
Start Date: 2022-08-15
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 100
Treatments
Patient Group
Asymptomatic intracranial stenosis patients who receive standard medical treatment without stenting
Healthy Control
Healthy control are free from intracranial stenosis
Related Therapeutic Areas
Sponsors
Leads: Anhui Medical University