Change of Hemodynamics and Cerebral Functions After Carotid Artery Revascularization

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The majority (\>80%) of strokes are of ischemic etiology, of which ≈15% to 20% are attributable to atherosclerosis of the extracranial carotid arteries. The primary goal in carotid artery revascularization is to prevent stroke in patients with carotid artery stenosis. Treatment options including carotid endarterectomy (CEA) and carotid artery stenting (CAS). Hence, the investigators aim to compare carotid artery stenting (CAS) with carotid endarterectomy (CEA) in terms of long-term prognostic endpoints. Also, CEA and CAS result in different postoperative geometric features of carotid arteries that entail relevant modifications of rheological parameters, that may be associated with the risk of local complications and carotid artery restenosis. Finally, long-term and sustained cognitive benefits after carotid artery revascularization need further research and evidence.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: f
View:

• Informed consent signed Patients with \>=70% symptomatic or \>=80% asymptomatic internal carotid stenosis

Locations
Other Locations
China
Beijing Friendship Hospital, Capital Medical University
RECRUITING
Beijing
Contact Information
Primary
Mingyuan Liu, PhD
dr.mingyuanliu@pku.edu.cn
+8613011157272
Time Frame
Start Date: 2020-01-01
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 200
Sponsors
Leads: Beijing Friendship Hospital

This content was sourced from clinicaltrials.gov